A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission

A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission

Mosquito saliva can affect transmission of Plasmodium to mammalian hosts, but active saliva components or mechanisms are poorly understood. Here, the authors identify a mosquito saliva protein that binds Plasmodium sporozoites and inhibits cell traversal in vitro and sporozoite speed in mice.

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Detalles Bibliográficos
Autores principales: Tyler R. Schleicher, Jing Yang, Marianna Freudzon, Alison Rembisz, Samuel Craft, Madeleine Hamilton, Morven Graham, Godfree Mlambo, Abhai K. Tripathi, Yue Li, Peter Cresswell, Photini Sinnis, George Dimopoulos, Erol Fikrig
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/6f1de94305704e90b23021c6aaa9d413
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