Procr-expressing progenitor cells are responsible for murine ovulatory rupture repair of ovarian surface epithelium

The ovary is covered by a surface epithelium (OSE) and cells mediating its repair post ovulation are unclear. Here, the authors identify the Protein C Receptor (Procr) as marking progenitor cells, distinct from Lgr5+ stem cells, on the murine surface epithelium that repair the OSE post ovulation.

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Detalles Bibliográficos
Autores principales: Jingqiang Wang, Daisong Wang, Kun Chu, Wen Li, Yi Arial Zeng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/6f1f50cae3e74f57ac19f7ba36053a93
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Sumario:The ovary is covered by a surface epithelium (OSE) and cells mediating its repair post ovulation are unclear. Here, the authors identify the Protein C Receptor (Procr) as marking progenitor cells, distinct from Lgr5+ stem cells, on the murine surface epithelium that repair the OSE post ovulation.