Reliable evaluation method of heating power of magnetic nanofluids to directly predict the tumor temperature during hyperthermia

Abstract Reliable measurement of heating power of magnetic nanofluids (MNs) to accurately predict the AC heat-induction performance in tumors is highly desirable for clinical magnetic nanofluids hyperthermia (MNFH) application because it can save time for screening the performance of newly developed...

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Autores principales:	Ji-wook Kim, Seongtae Bae
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6f2454be95c14dd9988839386bf4a7b3
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spelling	oai:doaj.org-article:6f2454be95c14dd9988839386bf4a7b32021-11-14T12:18:55ZReliable evaluation method of heating power of magnetic nanofluids to directly predict the tumor temperature during hyperthermia10.1038/s41598-021-01321-32045-2322https://doaj.org/article/6f2454be95c14dd9988839386bf4a7b32021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-01321-3https://doaj.org/toc/2045-2322Abstract Reliable measurement of heating power of magnetic nanofluids (MNs) to accurately predict the AC heat-induction performance in tumors is highly desirable for clinical magnetic nanofluids hyperthermia (MNFH) application because it can save time for screening the performance of newly developed MNFH agent and minimize the over-use of animals dramatically. Here, a bio-mimicking phantom model, called Pseudo-Tumor Environment System (P-TES), biochemically designed by considering the external and internal critical factors related to the complex biological environments is proposed to provide a highly reliable evaluation method of heating performance of MNs for in-vivo MNFH applications. According to the experimentally analyzed results, the heating power of MNs measured using the P-TES is well accorded with the heating temperature measured in the tumors during in-vivo MNFH. This result strongly demonstrates that the proposed P-TES can be recommended as a standardized measurement method of heating performance of MNs for clinical MNFH application.Ji-wook KimSeongtae BaeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ji-wook Kim Seongtae Bae Reliable evaluation method of heating power of magnetic nanofluids to directly predict the tumor temperature during hyperthermia
description	Abstract Reliable measurement of heating power of magnetic nanofluids (MNs) to accurately predict the AC heat-induction performance in tumors is highly desirable for clinical magnetic nanofluids hyperthermia (MNFH) application because it can save time for screening the performance of newly developed MNFH agent and minimize the over-use of animals dramatically. Here, a bio-mimicking phantom model, called Pseudo-Tumor Environment System (P-TES), biochemically designed by considering the external and internal critical factors related to the complex biological environments is proposed to provide a highly reliable evaluation method of heating performance of MNs for in-vivo MNFH applications. According to the experimentally analyzed results, the heating power of MNs measured using the P-TES is well accorded with the heating temperature measured in the tumors during in-vivo MNFH. This result strongly demonstrates that the proposed P-TES can be recommended as a standardized measurement method of heating performance of MNs for clinical MNFH application.
format	article
author	Ji-wook Kim Seongtae Bae
author_facet	Ji-wook Kim Seongtae Bae
author_sort	Ji-wook Kim
title	Reliable evaluation method of heating power of magnetic nanofluids to directly predict the tumor temperature during hyperthermia
title_short	Reliable evaluation method of heating power of magnetic nanofluids to directly predict the tumor temperature during hyperthermia
title_full	Reliable evaluation method of heating power of magnetic nanofluids to directly predict the tumor temperature during hyperthermia
title_fullStr	Reliable evaluation method of heating power of magnetic nanofluids to directly predict the tumor temperature during hyperthermia
title_full_unstemmed	Reliable evaluation method of heating power of magnetic nanofluids to directly predict the tumor temperature during hyperthermia
title_sort	reliable evaluation method of heating power of magnetic nanofluids to directly predict the tumor temperature during hyperthermia
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6f2454be95c14dd9988839386bf4a7b3
work_keys_str_mv	AT jiwookkim reliableevaluationmethodofheatingpowerofmagneticnanofluidstodirectlypredictthetumortemperatureduringhyperthermia AT seongtaebae reliableevaluationmethodofheatingpowerofmagneticnanofluidstodirectlypredictthetumortemperatureduringhyperthermia
_version_	1718429293114032128

Reliable evaluation method of heating power of magnetic nanofluids to directly predict the tumor temperature during hyperthermia

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