Aldose reductase inhibitor increases doxorubicin-sensitivity of colon cancer cells and decreases cardiotoxicity
Abstract Anthracycline drugs such as doxorubicin (DOX) and daunorubicin remain some of the most active wide-spectrum and cost-effective drugs in cancer therapy. However, colorectal cancer (CRC) cells are inherently resistant to anthracyclines which at higher doses cause cardiotoxicity. Our recent st...
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Autores principales: | Himangshu Sonowal, Pabitra B. Pal, Jian-Jun Wen, Sanjay Awasthi, Kota V. Ramana, Satish K. Srivastava |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/6f2463b6cece423cb821de61b7c4f45e |
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