Digital variance angiography allows about 70% decrease of DSA-related radiation exposure in lower limb X-ray angiography

Abstract Our aim was to investigate whether the previously observed higher contrast-to-noise ratio (CNR) and better image quality of Digital Variance Angiography (DVA) - compared to Digital Subtraction Angiography (DSA) - can be used to reduce radiation exposure in lower limb X-ray angiography. This...

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Autores principales:	Marcell Gyánó, Márton Berczeli, Csaba Csobay-Novák, Dávid Szöllősi, Viktor I. Óriás, István Góg, János P. Kiss, Dániel S. Veres, Krisztián Szigeti, Szabolcs Osváth, Ákos Pataki, Viktória Juhász, Zoltán Oláh, Péter Sótonyi, Balázs Nemes
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6f285d513d0c4817af4480af0a0f865a
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spelling	oai:doaj.org-article:6f285d513d0c4817af4480af0a0f865a2021-11-14T12:17:48ZDigital variance angiography allows about 70% decrease of DSA-related radiation exposure in lower limb X-ray angiography10.1038/s41598-021-01208-32045-2322https://doaj.org/article/6f285d513d0c4817af4480af0a0f865a2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-01208-3https://doaj.org/toc/2045-2322Abstract Our aim was to investigate whether the previously observed higher contrast-to-noise ratio (CNR) and better image quality of Digital Variance Angiography (DVA) - compared to Digital Subtraction Angiography (DSA) - can be used to reduce radiation exposure in lower limb X-ray angiography. This prospective study enrolled 30 peripheral artery disease patients (mean ± SD age 70 ± 8 years) undergoing diagnostic angiography. In all patients, both normal (1.2 µGy/frame; 100%) and low-dose (0.36 µGy/frame; 30%) protocols were used for the acquisition of images in three anatomical regions (abdominal, femoral, crural). The CNR of DSA and DVA images were calculated, and the visual quality was evaluated by seven specialists using a 5-grade Likert scale. For investigating non-inferiority, the difference of low-dose DVA and normal dose DSA scores (DVA30-DSA100) was analyzed. DVA produced two- to three-fold CNR and significantly higher visual score than DSA. DVA30 proved to be superior to DSA100 in the crural region (difference 0.25 ± 0.07, p < 0.001), and there was no significant difference in the femoral (− 0.08 ± 0.06, p = 0.435) and abdominal (− 0.10 ± 0.09, p = 0.350) regions. Our data show that DVA allows about 70% reduction of DSA-related radiation exposure in lower limb X-ray angiography, providing a potential new radiation protection tool for the patients and the medical staff.Marcell GyánóMárton BerczeliCsaba Csobay-NovákDávid SzöllősiViktor I. ÓriásIstván GógJános P. KissDániel S. VeresKrisztián SzigetiSzabolcs OsváthÁkos PatakiViktória JuhászZoltán OláhPéter SótonyiBalázs NemesNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Marcell Gyánó Márton Berczeli Csaba Csobay-Novák Dávid Szöllősi Viktor I. Óriás István Góg János P. Kiss Dániel S. Veres Krisztián Szigeti Szabolcs Osváth Ákos Pataki Viktória Juhász Zoltán Oláh Péter Sótonyi Balázs Nemes Digital variance angiography allows about 70% decrease of DSA-related radiation exposure in lower limb X-ray angiography
description	Abstract Our aim was to investigate whether the previously observed higher contrast-to-noise ratio (CNR) and better image quality of Digital Variance Angiography (DVA) - compared to Digital Subtraction Angiography (DSA) - can be used to reduce radiation exposure in lower limb X-ray angiography. This prospective study enrolled 30 peripheral artery disease patients (mean ± SD age 70 ± 8 years) undergoing diagnostic angiography. In all patients, both normal (1.2 µGy/frame; 100%) and low-dose (0.36 µGy/frame; 30%) protocols were used for the acquisition of images in three anatomical regions (abdominal, femoral, crural). The CNR of DSA and DVA images were calculated, and the visual quality was evaluated by seven specialists using a 5-grade Likert scale. For investigating non-inferiority, the difference of low-dose DVA and normal dose DSA scores (DVA30-DSA100) was analyzed. DVA produced two- to three-fold CNR and significantly higher visual score than DSA. DVA30 proved to be superior to DSA100 in the crural region (difference 0.25 ± 0.07, p < 0.001), and there was no significant difference in the femoral (− 0.08 ± 0.06, p = 0.435) and abdominal (− 0.10 ± 0.09, p = 0.350) regions. Our data show that DVA allows about 70% reduction of DSA-related radiation exposure in lower limb X-ray angiography, providing a potential new radiation protection tool for the patients and the medical staff.
format	article
author	Marcell Gyánó Márton Berczeli Csaba Csobay-Novák Dávid Szöllősi Viktor I. Óriás István Góg János P. Kiss Dániel S. Veres Krisztián Szigeti Szabolcs Osváth Ákos Pataki Viktória Juhász Zoltán Oláh Péter Sótonyi Balázs Nemes
author_facet	Marcell Gyánó Márton Berczeli Csaba Csobay-Novák Dávid Szöllősi Viktor I. Óriás István Góg János P. Kiss Dániel S. Veres Krisztián Szigeti Szabolcs Osváth Ákos Pataki Viktória Juhász Zoltán Oláh Péter Sótonyi Balázs Nemes
author_sort	Marcell Gyánó
title	Digital variance angiography allows about 70% decrease of DSA-related radiation exposure in lower limb X-ray angiography
title_short	Digital variance angiography allows about 70% decrease of DSA-related radiation exposure in lower limb X-ray angiography
title_full	Digital variance angiography allows about 70% decrease of DSA-related radiation exposure in lower limb X-ray angiography
title_fullStr	Digital variance angiography allows about 70% decrease of DSA-related radiation exposure in lower limb X-ray angiography
title_full_unstemmed	Digital variance angiography allows about 70% decrease of DSA-related radiation exposure in lower limb X-ray angiography
title_sort	digital variance angiography allows about 70% decrease of dsa-related radiation exposure in lower limb x-ray angiography
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6f285d513d0c4817af4480af0a0f865a
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Digital variance angiography allows about 70% decrease of DSA-related radiation exposure in lower limb X-ray angiography

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