Are demographics associated with mucoepidermoid or acinic cell carcinoma parotid malignancies in children?

Objective: To identify possible associations between patient demographics and parotid cancer histological type in pediatric patients. Methods: Pediatric patients (ages: birth-18.0 years) in the Surveillance, Epidemiology, and End Results (SEER) database were included from 1973 to 2014 based on a dia...

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Autores principales: Tyler A. Janz, Eric J. Lentsch, Shaun A. Nguyen, Clarice S. Clemmens
Formato: article
Lenguaje:EN
Publicado: KeAi Communications Co., Ltd. 2019
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Acceso en línea:https://doaj.org/article/6f2bc9ad0b6f49178b9d7c2ac3c217c6
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spelling oai:doaj.org-article:6f2bc9ad0b6f49178b9d7c2ac3c217c62021-12-02T14:22:03ZAre demographics associated with mucoepidermoid or acinic cell carcinoma parotid malignancies in children?2095-881110.1016/j.wjorl.2019.05.002https://doaj.org/article/6f2bc9ad0b6f49178b9d7c2ac3c217c62019-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095881119301064https://doaj.org/toc/2095-8811Objective: To identify possible associations between patient demographics and parotid cancer histological type in pediatric patients. Methods: Pediatric patients (ages: birth-18.0 years) in the Surveillance, Epidemiology, and End Results (SEER) database were included from 1973 to 2014 based on a diagnosis of mucoepidermoid carcinoma or acinic cell carcinoma of the parotid gland using the ICD O-3 codes of C07.9 and 8430 or 8550. Patients were classified into the following cohorts: <14 and 14–18 years of age based on the mean age at diagnosis. Results: Three hundred and three pediatric patients were diagnosed with mucoepidermoid carcinoma or acinic cell carcinoma of the parotid gland within the SEER 18 registries. Female pediatric patients 14–18 years of age were 7.68 times more likely to have an acinic cell carcinoma (adjusted OR: 7.68 [95% CI: 2.01–29.44]). When stratified by histological type, 58.9% of female pediatric patients ≥14 years of age had an acinic cell carcinoma as compared to 37.3% of male pediatric patients ≥14 years of age, 36.5% of female pediatric patients <14 years of age, and 34.0% of male pediatric patients <14 years of age (P = 0.01). Conclusions: Based on this study, pediatric female patients between the ages of 14 and 18 years are the most likely cohort to have acinic cell carcinoma. The results of this study may assist providers during the work up of a pediatric patient with a suspected parotid malignancy. Keywords: Pediatric parotid cancer, Head and neck surgery, Pediatric otolaryngology, Level of evidence: 4Tyler A. JanzEric J. LentschShaun A. NguyenClarice S. ClemmensKeAi Communications Co., Ltd.articleOtorhinolaryngologyRF1-547SurgeryRD1-811ENWorld Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 5, Iss 4, Pp 222-227 (2019)
institution DOAJ
collection DOAJ
language EN
topic Otorhinolaryngology
RF1-547
Surgery
RD1-811
spellingShingle Otorhinolaryngology
RF1-547
Surgery
RD1-811
Tyler A. Janz
Eric J. Lentsch
Shaun A. Nguyen
Clarice S. Clemmens
Are demographics associated with mucoepidermoid or acinic cell carcinoma parotid malignancies in children?
description Objective: To identify possible associations between patient demographics and parotid cancer histological type in pediatric patients. Methods: Pediatric patients (ages: birth-18.0 years) in the Surveillance, Epidemiology, and End Results (SEER) database were included from 1973 to 2014 based on a diagnosis of mucoepidermoid carcinoma or acinic cell carcinoma of the parotid gland using the ICD O-3 codes of C07.9 and 8430 or 8550. Patients were classified into the following cohorts: <14 and 14–18 years of age based on the mean age at diagnosis. Results: Three hundred and three pediatric patients were diagnosed with mucoepidermoid carcinoma or acinic cell carcinoma of the parotid gland within the SEER 18 registries. Female pediatric patients 14–18 years of age were 7.68 times more likely to have an acinic cell carcinoma (adjusted OR: 7.68 [95% CI: 2.01–29.44]). When stratified by histological type, 58.9% of female pediatric patients ≥14 years of age had an acinic cell carcinoma as compared to 37.3% of male pediatric patients ≥14 years of age, 36.5% of female pediatric patients <14 years of age, and 34.0% of male pediatric patients <14 years of age (P = 0.01). Conclusions: Based on this study, pediatric female patients between the ages of 14 and 18 years are the most likely cohort to have acinic cell carcinoma. The results of this study may assist providers during the work up of a pediatric patient with a suspected parotid malignancy. Keywords: Pediatric parotid cancer, Head and neck surgery, Pediatric otolaryngology, Level of evidence: 4
format article
author Tyler A. Janz
Eric J. Lentsch
Shaun A. Nguyen
Clarice S. Clemmens
author_facet Tyler A. Janz
Eric J. Lentsch
Shaun A. Nguyen
Clarice S. Clemmens
author_sort Tyler A. Janz
title Are demographics associated with mucoepidermoid or acinic cell carcinoma parotid malignancies in children?
title_short Are demographics associated with mucoepidermoid or acinic cell carcinoma parotid malignancies in children?
title_full Are demographics associated with mucoepidermoid or acinic cell carcinoma parotid malignancies in children?
title_fullStr Are demographics associated with mucoepidermoid or acinic cell carcinoma parotid malignancies in children?
title_full_unstemmed Are demographics associated with mucoepidermoid or acinic cell carcinoma parotid malignancies in children?
title_sort are demographics associated with mucoepidermoid or acinic cell carcinoma parotid malignancies in children?
publisher KeAi Communications Co., Ltd.
publishDate 2019
url https://doaj.org/article/6f2bc9ad0b6f49178b9d7c2ac3c217c6
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