Relative Impact of Complement Receptors CD21/35 (Cr2/1) on Scrapie Pathogenesis in Mice
ABSTRACT Complement receptors 1 and 2 (CR1/2 or CD35/CD21) recognize complement-opsonized antigens to initiate innate and adaptive immunity, respectively. CD35 stimulates phagocytosis on macrophages and antigen presentation on follicular dendritic cells (FDCs). CD21 helps activate B cells as part of...
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Main Authors: | , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2017
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Subjects: | |
Online Access: | https://doaj.org/article/6f2c9ec8c79d4d4f811b088391cc4531 |
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