Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells
Plasmacytoid dendritic cells (pDCs) constitute a rare type of immune cell with multifaceted functions, but their potential use as a cell-based immunotherapy is challenged by the scarce cell numbers that can be extracted from blood. Here, we systematically investigate culture parameters for generatin...
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Main Authors: | Anders Laustsen, Renée M van der Sluis, Albert Gris-Oliver, Sabina Sánchez Hernández, Ena Cemalovic, Hai Q Tang, Lars Henning Pedersen, Niels Uldbjerg, Martin R Jakobsen, Rasmus O Bak |
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Format: | article |
Language: | EN |
Published: |
eLife Sciences Publications Ltd
2021
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Subjects: | |
Online Access: | https://doaj.org/article/6f3798286f634c3eb305fef770b61810 |
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