Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells

Plasmacytoid dendritic cells (pDCs) constitute a rare type of immune cell with multifaceted functions, but their potential use as a cell-based immunotherapy is challenged by the scarce cell numbers that can be extracted from blood. Here, we systematically investigate culture parameters for generatin...

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Bibliographic Details
Main Authors: Anders Laustsen, Renée M van der Sluis, Albert Gris-Oliver, Sabina Sánchez Hernández, Ena Cemalovic, Hai Q Tang, Lars Henning Pedersen, Niels Uldbjerg, Martin R Jakobsen, Rasmus O Bak
Format: article
Language:EN
Published: eLife Sciences Publications Ltd 2021
Subjects:
pDC
R
Q
Online Access:https://doaj.org/article/6f3798286f634c3eb305fef770b61810
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