ANTIOPHIDIAN PROPERTIES EVALUATION OF ETHANOL EXTRACTAND FRACTIONS OBTAINED FROM <i>Renealmia alpinia</i> (Rottb) Mass (<i>Zingiberaceae</i>)CULTIVATED in vitro.

Plant extracts are a rich source of pharmacologically active molecules. Their application allows a tradicional medicine approach to potential biological acitivities. This paper evaluates the inhibitory capacity of ethanolic extracts of leaves and little roots and also fractions chromatographically f...

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Autores principales:	Maritza FERNÁNDEZ C., William F. ORTIZ C., Jaime A. PEREÁÑEZ J., Diego MARTÍNEZ R
Formato:	article
Lenguaje:	EN
Publicado:	Universidad de Antioquia 2010
Materias:	Renealmia alpinia cultures in vitro fractions Bothrops asper antiophidian properties. Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675
Acceso en línea:	https://doaj.org/article/6f38cccefbfb4a9c87f79bcbbfca0cf9
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spelling	oai:doaj.org-article:6f38cccefbfb4a9c87f79bcbbfca0cf92021-11-19T04:14:38ZANTIOPHIDIAN PROPERTIES EVALUATION OF ETHANOL EXTRACTAND FRACTIONS OBTAINED FROM <i>Renealmia alpinia</i> (Rottb) Mass (<i>Zingiberaceae</i>)CULTIVATED in vitro.0121-40042145-2660https://doaj.org/article/6f38cccefbfb4a9c87f79bcbbfca0cf92010-03-01T00:00:00Zhttps://revistas.udea.edu.co/index.php/vitae/article/view/4979https://doaj.org/toc/0121-4004https://doaj.org/toc/2145-2660Plant extracts are a rich source of pharmacologically active molecules. Their application allows a tradicional medicine approach to potential biological acitivities. This paper evaluates the inhibitory capacity of ethanolic extracts of leaves and little roots and also fractions chromatographically fractions obtained from Renealmia alpinia (Rottb) Mass, cultured in vitro, on the indirect hemolytic activity, proteolytic activity and coagulant activity induced by the Bothrops asper venom. Indirect hemolytic activity is inhibited to a greater extent by the fraction 7-8 (47.3 ± 2.20%) followed in order by the extracts from little roots (32.6 ± 6.90%) and leaves (24.2 ± 4.43%). They came from in vitro and ex vitro leaves (16.2 ± 3.88%). The proteolytic activity is largely inhibited by the leaves extracts in vitro and ex vitro without significant differences between them. Little roots in vitro showed the highest neutralization effect on coagulant activity (81.73 ± 9.949s). Proteolytic activity from Renealmia alpinia extracts on Bothrops asper venom is ruled out since there are not changes in the electrophoretic pattern of the venom. The results make possible the implementation of Renealmia alpinia as adjuvant for the treatment of ophidic accidents and sustain the value of micropropagation for mass production of active components.Maritza FERNÁNDEZ C.William F. ORTIZ C.Jaime A. PEREÁÑEZ J.Diego MARTÍNEZ RUniversidad de AntioquiaarticleRenealmia alpiniacultures in vitrofractionsBothrops asperantiophidian properties.Food processing and manufactureTP368-456Pharmaceutical industryHD9665-9675ENVitae, Vol 17, Iss 1 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Renealmia alpinia cultures in vitro fractions Bothrops asper antiophidian properties. Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675
spellingShingle	Renealmia alpinia cultures in vitro fractions Bothrops asper antiophidian properties. Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675 Maritza FERNÁNDEZ C. William F. ORTIZ C. Jaime A. PEREÁÑEZ J. Diego MARTÍNEZ R ANTIOPHIDIAN PROPERTIES EVALUATION OF ETHANOL EXTRACTAND FRACTIONS OBTAINED FROM <i>Renealmia alpinia</i> (Rottb) Mass (<i>Zingiberaceae</i>)CULTIVATED in vitro.
description	Plant extracts are a rich source of pharmacologically active molecules. Their application allows a tradicional medicine approach to potential biological acitivities. This paper evaluates the inhibitory capacity of ethanolic extracts of leaves and little roots and also fractions chromatographically fractions obtained from Renealmia alpinia (Rottb) Mass, cultured in vitro, on the indirect hemolytic activity, proteolytic activity and coagulant activity induced by the Bothrops asper venom. Indirect hemolytic activity is inhibited to a greater extent by the fraction 7-8 (47.3 ± 2.20%) followed in order by the extracts from little roots (32.6 ± 6.90%) and leaves (24.2 ± 4.43%). They came from in vitro and ex vitro leaves (16.2 ± 3.88%). The proteolytic activity is largely inhibited by the leaves extracts in vitro and ex vitro without significant differences between them. Little roots in vitro showed the highest neutralization effect on coagulant activity (81.73 ± 9.949s). Proteolytic activity from Renealmia alpinia extracts on Bothrops asper venom is ruled out since there are not changes in the electrophoretic pattern of the venom. The results make possible the implementation of Renealmia alpinia as adjuvant for the treatment of ophidic accidents and sustain the value of micropropagation for mass production of active components.
format	article
author	Maritza FERNÁNDEZ C. William F. ORTIZ C. Jaime A. PEREÁÑEZ J. Diego MARTÍNEZ R
author_facet	Maritza FERNÁNDEZ C. William F. ORTIZ C. Jaime A. PEREÁÑEZ J. Diego MARTÍNEZ R
author_sort	Maritza FERNÁNDEZ C.
title	ANTIOPHIDIAN PROPERTIES EVALUATION OF ETHANOL EXTRACTAND FRACTIONS OBTAINED FROM <i>Renealmia alpinia</i> (Rottb) Mass (<i>Zingiberaceae</i>)CULTIVATED in vitro.
title_short	ANTIOPHIDIAN PROPERTIES EVALUATION OF ETHANOL EXTRACTAND FRACTIONS OBTAINED FROM <i>Renealmia alpinia</i> (Rottb) Mass (<i>Zingiberaceae</i>)CULTIVATED in vitro.
title_full	ANTIOPHIDIAN PROPERTIES EVALUATION OF ETHANOL EXTRACTAND FRACTIONS OBTAINED FROM <i>Renealmia alpinia</i> (Rottb) Mass (<i>Zingiberaceae</i>)CULTIVATED in vitro.
title_fullStr	ANTIOPHIDIAN PROPERTIES EVALUATION OF ETHANOL EXTRACTAND FRACTIONS OBTAINED FROM <i>Renealmia alpinia</i> (Rottb) Mass (<i>Zingiberaceae</i>)CULTIVATED in vitro.
title_full_unstemmed	ANTIOPHIDIAN PROPERTIES EVALUATION OF ETHANOL EXTRACTAND FRACTIONS OBTAINED FROM <i>Renealmia alpinia</i> (Rottb) Mass (<i>Zingiberaceae</i>)CULTIVATED in vitro.
title_sort	antiophidian properties evaluation of ethanol extractand fractions obtained from <i>renealmia alpinia</i> (rottb) mass (<i>zingiberaceae</i>)cultivated in vitro.
publisher	Universidad de Antioquia
publishDate	2010
url	https://doaj.org/article/6f38cccefbfb4a9c87f79bcbbfca0cf9
work_keys_str_mv	AT maritzafernandezc antiophidianpropertiesevaluationofethanolextractandfractionsobtainedfromirenealmiaalpiniairottbmassizingiberaceaeicultivatedinvitro AT williamfortizc antiophidianpropertiesevaluationofethanolextractandfractionsobtainedfromirenealmiaalpiniairottbmassizingiberaceaeicultivatedinvitro AT jaimeapereanezj antiophidianpropertiesevaluationofethanolextractandfractionsobtainedfromirenealmiaalpiniairottbmassizingiberaceaeicultivatedinvitro AT diegomartinezr antiophidianpropertiesevaluationofethanolextractandfractionsobtainedfromirenealmiaalpiniairottbmassizingiberaceaeicultivatedinvitro
_version_	1718420459651858432

ANTIOPHIDIAN PROPERTIES EVALUATION OF ETHANOL EXTRACTAND FRACTIONS OBTAINED FROM <i>Renealmia alpinia</i> (Rottb) Mass (<i>Zingiberaceae</i>)CULTIVATED in vitro.

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