Exploring the associations between transcript levels and fluxes in constraint-based models of metabolism
Abstract Background Several computational methods have been developed that integrate transcriptomics data with genome-scale metabolic reconstructions to increase accuracy of inferences of intracellular metabolic flux distributions. Even though existing methods use transcript abundances as a proxy fo...
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Autores principales: | Neeraj Sinha, Evert M. van Schothorst, Guido J. E. J. Hooiveld, Jaap Keijer, Vitor A. P. Martins dos Santos, Maria Suarez-Diez |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
BMC
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/6f4431891a6e4a50b5861b087c64c3c3 |
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