Exploring the associations between transcript levels and fluxes in constraint-based models of metabolism

Abstract Background Several computational methods have been developed that integrate transcriptomics data with genome-scale metabolic reconstructions to increase accuracy of inferences of intracellular metabolic flux distributions. Even though existing methods use transcript abundances as a proxy fo...

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Auteurs principaux: Neeraj Sinha, Evert M. van Schothorst, Guido J. E. J. Hooiveld, Jaap Keijer, Vitor A. P. Martins dos Santos, Maria Suarez-Diez
Format: article
Langue:EN
Publié: BMC 2021
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Accès en ligne:https://doaj.org/article/6f4431891a6e4a50b5861b087c64c3c3
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