FotoFinder Dermoscopy Analysis and Histopathological Correlation in Primary Localized Cutaneous Amyloidosis

Background: Primary localized cutaneous amyloidosis (PLCA) causes extracellular proteinaceous deposits in skin. It is clinically divided into macular amyloidosis, lichen amyloidosis and nodular amyloidosis. Atypical presentations of PLCA make the diagnosis challenging, requiring biopsy to confirm a...

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Autores principales:	Mahajabeen S. Madarkar, Varsha R. Koti
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2021
Materias:	macular amyloidosis lichen amyloidosis FotoFinder dermoscopy white rosettes Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/6f4b60920aea440ba11130bafca2c15a
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spelling	oai:doaj.org-article:6f4b60920aea440ba11130bafca2c15a2021-11-17T08:27:52ZFotoFinder Dermoscopy Analysis and Histopathological Correlation in Primary Localized Cutaneous Amyloidosis10.5826/dpc.1103a572160-9381https://doaj.org/article/6f4b60920aea440ba11130bafca2c15a2021-05-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/1601https://doaj.org/toc/2160-9381 Background: Primary localized cutaneous amyloidosis (PLCA) causes extracellular proteinaceous deposits in skin. It is clinically divided into macular amyloidosis, lichen amyloidosis and nodular amyloidosis. Atypical presentations of PLCA make the diagnosis challenging, requiring biopsy to confirm amyloid deposition in the upper papillary dermis. Objectives: This study used FotoFinder dermoscopy to characterize lichen and macular amyloidosis and correlated the dermoscopic features with histopathological findings. Methods: This cross-sectional study enrolled patients with a clinical and histopathological diagnosis of PLCA. Dermoscopic examination was performed using the FotoFinder dermoscope, which provides a range of magnification from 20´ to 140´. Results: A total of 30 patients were included in the study. Common dermoscopic patterns of MA were white or brown central hubs, and common patterns of LA were white structureless, scar-like areas and central hubs. New dermoscopic findings were a day lily appearance in MA and white rosettes in LA. Conclusions: Dermoscopy plays a pivotal role in demonstrating characteristic findings of PLCA. These findings were well corelated with histopathology, thus avoiding unnecessary biopsy for arriving at an accurate diagnosis of PLCA. Mahajabeen S. MadarkarVarsha R. KotiMattioli1885articlemacular amyloidosislichen amyloidosisFotoFinder dermoscopywhite rosettesDermatologyRL1-803ENDermatology Practical & Conceptual (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	macular amyloidosis lichen amyloidosis FotoFinder dermoscopy white rosettes Dermatology RL1-803
spellingShingle	macular amyloidosis lichen amyloidosis FotoFinder dermoscopy white rosettes Dermatology RL1-803 Mahajabeen S. Madarkar Varsha R. Koti FotoFinder Dermoscopy Analysis and Histopathological Correlation in Primary Localized Cutaneous Amyloidosis
description	Background: Primary localized cutaneous amyloidosis (PLCA) causes extracellular proteinaceous deposits in skin. It is clinically divided into macular amyloidosis, lichen amyloidosis and nodular amyloidosis. Atypical presentations of PLCA make the diagnosis challenging, requiring biopsy to confirm amyloid deposition in the upper papillary dermis. Objectives: This study used FotoFinder dermoscopy to characterize lichen and macular amyloidosis and correlated the dermoscopic features with histopathological findings. Methods: This cross-sectional study enrolled patients with a clinical and histopathological diagnosis of PLCA. Dermoscopic examination was performed using the FotoFinder dermoscope, which provides a range of magnification from 20´ to 140´. Results: A total of 30 patients were included in the study. Common dermoscopic patterns of MA were white or brown central hubs, and common patterns of LA were white structureless, scar-like areas and central hubs. New dermoscopic findings were a day lily appearance in MA and white rosettes in LA. Conclusions: Dermoscopy plays a pivotal role in demonstrating characteristic findings of PLCA. These findings were well corelated with histopathology, thus avoiding unnecessary biopsy for arriving at an accurate diagnosis of PLCA.
format	article
author	Mahajabeen S. Madarkar Varsha R. Koti
author_facet	Mahajabeen S. Madarkar Varsha R. Koti
author_sort	Mahajabeen S. Madarkar
title	FotoFinder Dermoscopy Analysis and Histopathological Correlation in Primary Localized Cutaneous Amyloidosis
title_short	FotoFinder Dermoscopy Analysis and Histopathological Correlation in Primary Localized Cutaneous Amyloidosis
title_full	FotoFinder Dermoscopy Analysis and Histopathological Correlation in Primary Localized Cutaneous Amyloidosis
title_fullStr	FotoFinder Dermoscopy Analysis and Histopathological Correlation in Primary Localized Cutaneous Amyloidosis
title_full_unstemmed	FotoFinder Dermoscopy Analysis and Histopathological Correlation in Primary Localized Cutaneous Amyloidosis
title_sort	fotofinder dermoscopy analysis and histopathological correlation in primary localized cutaneous amyloidosis
publisher	Mattioli1885
publishDate	2021
url	https://doaj.org/article/6f4b60920aea440ba11130bafca2c15a
work_keys_str_mv	AT mahajabeensmadarkar fotofinderdermoscopyanalysisandhistopathologicalcorrelationinprimarylocalizedcutaneousamyloidosis AT varsharkoti fotofinderdermoscopyanalysisandhistopathologicalcorrelationinprimarylocalizedcutaneousamyloidosis
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FotoFinder Dermoscopy Analysis and Histopathological Correlation in Primary Localized Cutaneous Amyloidosis

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