Fibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly

Multicilia are complex, and how they achieve accurate assembly is unclear. Here, the authors show that fibrogranular materials condense into spherical cores and function in multicilia formation by tightly associating with deuterosomes and concentrating specific proteins to promote proper assembly.

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Autores principales:	Huijie Zhao, Qingxia Chen, Fan Li, Lihong Cui, Lele Xie, Qiongping Huang, Xin Liang, Jun Zhou, Xiumin Yan, Xueliang Zhu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6f4f51dc616d4b5aba7faacd792d48c2
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spelling	oai:doaj.org-article:6f4f51dc616d4b5aba7faacd792d48c22021-12-02T13:32:51ZFibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly10.1038/s41467-021-21506-82041-1723https://doaj.org/article/6f4f51dc616d4b5aba7faacd792d48c22021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21506-8https://doaj.org/toc/2041-1723Multicilia are complex, and how they achieve accurate assembly is unclear. Here, the authors show that fibrogranular materials condense into spherical cores and function in multicilia formation by tightly associating with deuterosomes and concentrating specific proteins to promote proper assembly.Huijie ZhaoQingxia ChenFan LiLihong CuiLele XieQiongping HuangXin LiangJun ZhouXiumin YanXueliang ZhuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Huijie Zhao Qingxia Chen Fan Li Lihong Cui Lele Xie Qiongping Huang Xin Liang Jun Zhou Xiumin Yan Xueliang Zhu Fibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly
description	Multicilia are complex, and how they achieve accurate assembly is unclear. Here, the authors show that fibrogranular materials condense into spherical cores and function in multicilia formation by tightly associating with deuterosomes and concentrating specific proteins to promote proper assembly.
format	article
author	Huijie Zhao Qingxia Chen Fan Li Lihong Cui Lele Xie Qiongping Huang Xin Liang Jun Zhou Xiumin Yan Xueliang Zhu
author_facet	Huijie Zhao Qingxia Chen Fan Li Lihong Cui Lele Xie Qiongping Huang Xin Liang Jun Zhou Xiumin Yan Xueliang Zhu
author_sort	Huijie Zhao
title	Fibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly
title_short	Fibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly
title_full	Fibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly
title_fullStr	Fibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly
title_full_unstemmed	Fibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly
title_sort	fibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6f4f51dc616d4b5aba7faacd792d48c2
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Fibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly

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