Solitary Fibrous Tumor of the Prostate: A Case Report and Literature Review

Solitary fibrous tumors (SFTs) usually occur in the pleura and account for two-thirds of all cases; however, SFTs occurring in the prostate are extremely rare. Approximately 25 cases have been reported in the literature to date. This study reports the case of a 43-year-old man referred to our hospit...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yasumichi Takeuchi, Daiki Kato, Keita Nakane, Kota Kawase, Manabu Takai, Koji Iinuma, Chiemi Saigo, Tatsuhiko Miyazaki, Takuya Koie
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	prostatic tumor solitary fibrous tumor rare case case report Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/6f4fdd1f31a94be19b5056dcfb842baa
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6f4fdd1f31a94be19b5056dcfb842baa
record_format	dspace
spelling	oai:doaj.org-article:6f4fdd1f31a94be19b5056dcfb842baa2021-11-25T18:18:07ZSolitary Fibrous Tumor of the Prostate: A Case Report and Literature Review10.3390/medicina571111521648-91441010-660Xhttps://doaj.org/article/6f4fdd1f31a94be19b5056dcfb842baa2021-10-01T00:00:00Zhttps://www.mdpi.com/1648-9144/57/11/1152https://doaj.org/toc/1010-660Xhttps://doaj.org/toc/1648-9144Solitary fibrous tumors (SFTs) usually occur in the pleura and account for two-thirds of all cases; however, SFTs occurring in the prostate are extremely rare. Approximately 25 cases have been reported in the literature to date. This study reports the case of a 43-year-old man referred to our hospital with the chief complaint of a pelvic tumor after careful examination. The tumor marker levels were within normal limits. T2-weighted magnetic resonance imaging revealed a tumor, demonstrating primarily low signal intensity. It showed a capsule-like rim at the left lobe of the prostate, suggesting that the tumor was partially invading the rectal wall. Histopathological examination of needle-core biopsies showed spindle cell neoplasm with small and fusiform cells, strongly expressing signal transducer and activator of transcription 6 (STAT6) with a ramifying vascular network. Therefore, the clinical diagnosis of the patient was SFT of the prostate and robot-assisted radical prostatectomy was performed. Histopathological examination revealed that the tumor was composed of spindle cells with patternless and staghorn patterns. Immunohistochemical analysis showed a strong expression of STAT6. Furthermore, the tumor was partially positive for CD34. Therefore, the patient was diagnosed with SFT of the prostate. Two years after the initial diagnosis, the patient was alive with normal erectile function, continence status, and no evidence of the disease.Yasumichi TakeuchiDaiki KatoKeita NakaneKota KawaseManabu TakaiKoji IinumaChiemi SaigoTatsuhiko MiyazakiTakuya KoieMDPI AGarticleprostatic tumorsolitary fibrous tumorrare casecase reportMedicine (General)R5-920ENMedicina, Vol 57, Iss 1152, p 1152 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	prostatic tumor solitary fibrous tumor rare case case report Medicine (General) R5-920
spellingShingle	prostatic tumor solitary fibrous tumor rare case case report Medicine (General) R5-920 Yasumichi Takeuchi Daiki Kato Keita Nakane Kota Kawase Manabu Takai Koji Iinuma Chiemi Saigo Tatsuhiko Miyazaki Takuya Koie Solitary Fibrous Tumor of the Prostate: A Case Report and Literature Review
description	Solitary fibrous tumors (SFTs) usually occur in the pleura and account for two-thirds of all cases; however, SFTs occurring in the prostate are extremely rare. Approximately 25 cases have been reported in the literature to date. This study reports the case of a 43-year-old man referred to our hospital with the chief complaint of a pelvic tumor after careful examination. The tumor marker levels were within normal limits. T2-weighted magnetic resonance imaging revealed a tumor, demonstrating primarily low signal intensity. It showed a capsule-like rim at the left lobe of the prostate, suggesting that the tumor was partially invading the rectal wall. Histopathological examination of needle-core biopsies showed spindle cell neoplasm with small and fusiform cells, strongly expressing signal transducer and activator of transcription 6 (STAT6) with a ramifying vascular network. Therefore, the clinical diagnosis of the patient was SFT of the prostate and robot-assisted radical prostatectomy was performed. Histopathological examination revealed that the tumor was composed of spindle cells with patternless and staghorn patterns. Immunohistochemical analysis showed a strong expression of STAT6. Furthermore, the tumor was partially positive for CD34. Therefore, the patient was diagnosed with SFT of the prostate. Two years after the initial diagnosis, the patient was alive with normal erectile function, continence status, and no evidence of the disease.
format	article
author	Yasumichi Takeuchi Daiki Kato Keita Nakane Kota Kawase Manabu Takai Koji Iinuma Chiemi Saigo Tatsuhiko Miyazaki Takuya Koie
author_facet	Yasumichi Takeuchi Daiki Kato Keita Nakane Kota Kawase Manabu Takai Koji Iinuma Chiemi Saigo Tatsuhiko Miyazaki Takuya Koie
author_sort	Yasumichi Takeuchi
title	Solitary Fibrous Tumor of the Prostate: A Case Report and Literature Review
title_short	Solitary Fibrous Tumor of the Prostate: A Case Report and Literature Review
title_full	Solitary Fibrous Tumor of the Prostate: A Case Report and Literature Review
title_fullStr	Solitary Fibrous Tumor of the Prostate: A Case Report and Literature Review
title_full_unstemmed	Solitary Fibrous Tumor of the Prostate: A Case Report and Literature Review
title_sort	solitary fibrous tumor of the prostate: a case report and literature review
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/6f4fdd1f31a94be19b5056dcfb842baa
work_keys_str_mv	AT yasumichitakeuchi solitaryfibroustumoroftheprostateacasereportandliteraturereview AT daikikato solitaryfibroustumoroftheprostateacasereportandliteraturereview AT keitanakane solitaryfibroustumoroftheprostateacasereportandliteraturereview AT kotakawase solitaryfibroustumoroftheprostateacasereportandliteraturereview AT manabutakai solitaryfibroustumoroftheprostateacasereportandliteraturereview AT kojiiinuma solitaryfibroustumoroftheprostateacasereportandliteraturereview AT chiemisaigo solitaryfibroustumoroftheprostateacasereportandliteraturereview AT tatsuhikomiyazaki solitaryfibroustumoroftheprostateacasereportandliteraturereview AT takuyakoie solitaryfibroustumoroftheprostateacasereportandliteraturereview
_version_	1718411387470872576

Solitary Fibrous Tumor of the Prostate: A Case Report and Literature Review

Ejemplares similares