A polymeric nanomedicine diminishes inflammatory events in renal tubular cells.
The polyglutamic acid/peptoid 1 (QM56) nanoconjugate inhibits apoptosis by interfering with Apaf-1 binding to procaspase-9. We now describe anti-inflammatory properties of QM56 in mouse kidney and renal cell models.In cultured murine tubular cells, QM56 inhibited the inflammatory response to Tweak,...
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Autores principales: | Alvaro C Ucero, Sergio Berzal, Carlos Ocaña-Salceda, Mónica Sancho, Mar Orzáez, Angel Messeguer, Marta Ruiz-Ortega, Jesús Egido, María J Vicent, Alberto Ortiz, Adrián M Ramos |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/6f5a9a96097b45528fc4ebcc8d5f0ccc |
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