Recent Developments in Diagnosis of Epilepsy: Scope of MicroRNA and Technological Advancements

Epilepsy is one of the most common neurological disorders, characterized by recurrent seizures, resulting from abnormally synchronized episodic neuronal discharges. Around 70 million people worldwide are suffering from epilepsy. The available antiepileptic medications are capable of controlling seiz...

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Autores principales:	Ritam Bandopadhyay, Tanveer Singh, Mohammed M. Ghoneim, Sultan Alshehri, Efthalia Angelopoulou, Yam Nath Paudel, Christina Piperi, Javed Ahmad, Nabil A. Alhakamy, Mohamed A. Alfaleh, Awanish Mishra
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	epilepsy diagnosis EEG CT MRI PET Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/6f5b76804bef46cd9ab0a980f0cb5e42
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spelling	oai:doaj.org-article:6f5b76804bef46cd9ab0a980f0cb5e422021-11-25T16:46:58ZRecent Developments in Diagnosis of Epilepsy: Scope of MicroRNA and Technological Advancements10.3390/biology101110972079-7737https://doaj.org/article/6f5b76804bef46cd9ab0a980f0cb5e422021-10-01T00:00:00Zhttps://www.mdpi.com/2079-7737/10/11/1097https://doaj.org/toc/2079-7737Epilepsy is one of the most common neurological disorders, characterized by recurrent seizures, resulting from abnormally synchronized episodic neuronal discharges. Around 70 million people worldwide are suffering from epilepsy. The available antiepileptic medications are capable of controlling seizures in around 60–70% of patients, while the rest remain refractory. Poor seizure control is often associated with neuro-psychiatric comorbidities, mainly including memory impairment, depression, psychosis, neurodegeneration, motor impairment, neuroendocrine dysfunction, etc., resulting in poor prognosis. Effective treatment relies on early and correct detection of epileptic foci. Although there are currently a few well-established diagnostic techniques for epilepsy, they lack accuracy and cannot be applied to patients who are unsupportive or harbor metallic implants. Since a single test result from one of these techniques does not provide complete information about the epileptic foci, it is necessary to develop novel diagnostic tools. Herein, we provide a comprehensive overview of the current diagnostic tools of epilepsy, including electroencephalography (EEG) as well as structural and functional neuroimaging. We further discuss recent trends and advances in the diagnosis of epilepsy that will enable more effective diagnosis and clinical management of patients.Ritam BandopadhyayTanveer SinghMohammed M. GhoneimSultan AlshehriEfthalia AngelopoulouYam Nath PaudelChristina PiperiJaved AhmadNabil A. AlhakamyMohamed A. AlfalehAwanish MishraMDPI AGarticleepilepsydiagnosisEEGCTMRIPETBiology (General)QH301-705.5ENBiology, Vol 10, Iss 1097, p 1097 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	epilepsy diagnosis EEG CT MRI PET Biology (General) QH301-705.5
spellingShingle	epilepsy diagnosis EEG CT MRI PET Biology (General) QH301-705.5 Ritam Bandopadhyay Tanveer Singh Mohammed M. Ghoneim Sultan Alshehri Efthalia Angelopoulou Yam Nath Paudel Christina Piperi Javed Ahmad Nabil A. Alhakamy Mohamed A. Alfaleh Awanish Mishra Recent Developments in Diagnosis of Epilepsy: Scope of MicroRNA and Technological Advancements
description	Epilepsy is one of the most common neurological disorders, characterized by recurrent seizures, resulting from abnormally synchronized episodic neuronal discharges. Around 70 million people worldwide are suffering from epilepsy. The available antiepileptic medications are capable of controlling seizures in around 60–70% of patients, while the rest remain refractory. Poor seizure control is often associated with neuro-psychiatric comorbidities, mainly including memory impairment, depression, psychosis, neurodegeneration, motor impairment, neuroendocrine dysfunction, etc., resulting in poor prognosis. Effective treatment relies on early and correct detection of epileptic foci. Although there are currently a few well-established diagnostic techniques for epilepsy, they lack accuracy and cannot be applied to patients who are unsupportive or harbor metallic implants. Since a single test result from one of these techniques does not provide complete information about the epileptic foci, it is necessary to develop novel diagnostic tools. Herein, we provide a comprehensive overview of the current diagnostic tools of epilepsy, including electroencephalography (EEG) as well as structural and functional neuroimaging. We further discuss recent trends and advances in the diagnosis of epilepsy that will enable more effective diagnosis and clinical management of patients.
format	article
author	Ritam Bandopadhyay Tanveer Singh Mohammed M. Ghoneim Sultan Alshehri Efthalia Angelopoulou Yam Nath Paudel Christina Piperi Javed Ahmad Nabil A. Alhakamy Mohamed A. Alfaleh Awanish Mishra
author_facet	Ritam Bandopadhyay Tanveer Singh Mohammed M. Ghoneim Sultan Alshehri Efthalia Angelopoulou Yam Nath Paudel Christina Piperi Javed Ahmad Nabil A. Alhakamy Mohamed A. Alfaleh Awanish Mishra
author_sort	Ritam Bandopadhyay
title	Recent Developments in Diagnosis of Epilepsy: Scope of MicroRNA and Technological Advancements
title_short	Recent Developments in Diagnosis of Epilepsy: Scope of MicroRNA and Technological Advancements
title_full	Recent Developments in Diagnosis of Epilepsy: Scope of MicroRNA and Technological Advancements
title_fullStr	Recent Developments in Diagnosis of Epilepsy: Scope of MicroRNA and Technological Advancements
title_full_unstemmed	Recent Developments in Diagnosis of Epilepsy: Scope of MicroRNA and Technological Advancements
title_sort	recent developments in diagnosis of epilepsy: scope of microrna and technological advancements
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/6f5b76804bef46cd9ab0a980f0cb5e42
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Recent Developments in Diagnosis of Epilepsy: Scope of MicroRNA and Technological Advancements

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