Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases

Mutations in TP53 gene are very common in cancer development. Here the authors take advantage of murine models to show that somatic Trp53 mutations differentially drive breast cancer and evolution of metastases.

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Detalles Bibliográficos
Autores principales:	Yun Zhang, Shunbin Xiong, Bin Liu, Vinod Pant, Francis Celii, Gilda Chau, Ana C. Elizondo-Fraire, Peirong Yang, Mingjian James You, Adel K. El-Naggar, Nicholas E. Navin, Guillermina Lozano
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6f7368c1d73241eeac39f0f8b051d0b9
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spelling	oai:doaj.org-article:6f7368c1d73241eeac39f0f8b051d0b92021-12-02T17:31:59ZSomatic Trp53 mutations differentially drive breast cancer and evolution of metastases10.1038/s41467-018-06146-92041-1723https://doaj.org/article/6f7368c1d73241eeac39f0f8b051d0b92018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06146-9https://doaj.org/toc/2041-1723Mutations in TP53 gene are very common in cancer development. Here the authors take advantage of murine models to show that somatic Trp53 mutations differentially drive breast cancer and evolution of metastases.Yun ZhangShunbin XiongBin LiuVinod PantFrancis CeliiGilda ChauAna C. Elizondo-FrairePeirong YangMingjian James YouAdel K. El-NaggarNicholas E. NavinGuillermina LozanoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yun Zhang Shunbin Xiong Bin Liu Vinod Pant Francis Celii Gilda Chau Ana C. Elizondo-Fraire Peirong Yang Mingjian James You Adel K. El-Naggar Nicholas E. Navin Guillermina Lozano Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases
description	Mutations in TP53 gene are very common in cancer development. Here the authors take advantage of murine models to show that somatic Trp53 mutations differentially drive breast cancer and evolution of metastases.
format	article
author	Yun Zhang Shunbin Xiong Bin Liu Vinod Pant Francis Celii Gilda Chau Ana C. Elizondo-Fraire Peirong Yang Mingjian James You Adel K. El-Naggar Nicholas E. Navin Guillermina Lozano
author_facet	Yun Zhang Shunbin Xiong Bin Liu Vinod Pant Francis Celii Gilda Chau Ana C. Elizondo-Fraire Peirong Yang Mingjian James You Adel K. El-Naggar Nicholas E. Navin Guillermina Lozano
author_sort	Yun Zhang
title	Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases
title_short	Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases
title_full	Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases
title_fullStr	Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases
title_full_unstemmed	Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases
title_sort	somatic trp53 mutations differentially drive breast cancer and evolution of metastases
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/6f7368c1d73241eeac39f0f8b051d0b9
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Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases

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