Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs

Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs

Zelda is a pioneer factor that regulates transcription in Drosophila embryos. Here, the authors use quantitative live imaging and mathematical modeling to measure the effect of Zelda on transcriptional dynamics and memory, observing temporal control of gene expression by Zelda through transient inte...

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Autores principales: Jeremy Dufourt, Antonio Trullo, Jennifer Hunter, Carola Fernandez, Jorge Lazaro, Matthieu Dejean, Lucas Morales, Saida Nait-Amer, Katharine N. Schulz, Melissa M. Harrison, Cyril Favard, Ovidiu Radulescu, Mounia Lagha
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/6f73d116eb0e46649c4a65fbc2648168
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spelling oai:doaj.org-article:6f73d116eb0e46649c4a65fbc26481682021-12-02T15:34:42ZTemporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs10.1038/s41467-018-07613-z2041-1723https://doaj.org/article/6f73d116eb0e46649c4a65fbc26481682018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07613-zhttps://doaj.org/toc/2041-1723Zelda is a pioneer factor that regulates transcription in Drosophila embryos. Here, the authors use quantitative live imaging and mathematical modeling to measure the effect of Zelda on transcriptional dynamics and memory, observing temporal control of gene expression by Zelda through transient interactions in hubs.Jeremy DufourtAntonio TrulloJennifer HunterCarola FernandezJorge LazaroMatthieu DejeanLucas MoralesSaida Nait-AmerKatharine N. SchulzMelissa M. HarrisonCyril FavardOvidiu RadulescuMounia LaghaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jeremy Dufourt
Antonio Trullo
Jennifer Hunter
Carola Fernandez
Jorge Lazaro
Matthieu Dejean
Lucas Morales
Saida Nait-Amer
Katharine N. Schulz
Melissa M. Harrison
Cyril Favard
Ovidiu Radulescu
Mounia Lagha
Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs
description Zelda is a pioneer factor that regulates transcription in Drosophila embryos. Here, the authors use quantitative live imaging and mathematical modeling to measure the effect of Zelda on transcriptional dynamics and memory, observing temporal control of gene expression by Zelda through transient interactions in hubs.
format article
author Jeremy Dufourt
Antonio Trullo
Jennifer Hunter
Carola Fernandez
Jorge Lazaro
Matthieu Dejean
Lucas Morales
Saida Nait-Amer
Katharine N. Schulz
Melissa M. Harrison
Cyril Favard
Ovidiu Radulescu
Mounia Lagha
author_facet Jeremy Dufourt
Antonio Trullo
Jennifer Hunter
Carola Fernandez
Jorge Lazaro
Matthieu Dejean
Lucas Morales
Saida Nait-Amer
Katharine N. Schulz
Melissa M. Harrison
Cyril Favard
Ovidiu Radulescu
Mounia Lagha
author_sort Jeremy Dufourt
title Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs
title_short Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs
title_full Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs
title_fullStr Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs
title_full_unstemmed Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs
title_sort temporal control of gene expression by the pioneer factor zelda through transient interactions in hubs
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/6f73d116eb0e46649c4a65fbc2648168
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