CD157 Confers Host Resistance to <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> via TLR2-CD157-PKCzeta-Induced Reactive Oxygen Species Production

CD157 Confers Host Resistance to <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> via TLR2-CD157-PKCzeta-Induced Reactive Oxygen Species Production

ABSTRACT Recruitment of monocytes to the infection site is critical for host resistance against Mycobacterium tuberculosis. CD157 has a crucial role in neutrophil and monocyte transendothelial migration and adhesion, but its role in tuberculosis (TB) is unclear. Here, we show that both mRNA and prot...

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Autores principales: Qianting Yang, Mingfeng Liao, Wenfei Wang, Mingxia Zhang, Qi Chen, Jiubiao Guo, Bin Peng, Jian Huang, Haiying Liu, Ayano Yahagi, Xingzhi Xu, Katsuhiko Ishihara, Andrea Cooper, Xinchun Chen, Yi Cai
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
CD157
Mycobacterium tuberculosis
PKCzeta
TLR2
reactive oxygen species
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/6f7481f533f041d985548ff9000e8852
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