Promotion of Surgical Masks Antimicrobial Activity by Disinfection and Impregnation with Disinfectant Silver Nanoparticles

Benjamin Valdez-Salas,1,2 Ernesto Beltran-Partida,1,2 Nelson Cheng,3 Jorge Salvador-Carlos,2 Ernesto Alonso Valdez-Salas,1 Mario Curiel-Alvarez,2 Roberto Ibarra-Wiley2 1Laboratorio de Biología Molecular y Cáncer, Instituto de Ingeniería, Universidad Autóno...

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Autores principales:	Valdez-Salas B, Beltran-Partida E, Cheng N, Salvador-Carlos J, Valdez-Salas EA, Curiel-Alvarez M, Ibarra-Wiley R
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	surgical mask antimicrobial sars-cov-2 nanobiotechnology covid-19 nanoparticles Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/6f7587f8362f4e4f83d2ebba14ba7ac6
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spelling	oai:doaj.org-article:6f7587f8362f4e4f83d2ebba14ba7ac62021-12-02T15:40:56ZPromotion of Surgical Masks Antimicrobial Activity by Disinfection and Impregnation with Disinfectant Silver Nanoparticles1178-2013https://doaj.org/article/6f7587f8362f4e4f83d2ebba14ba7ac62021-04-01T00:00:00Zhttps://www.dovepress.com/promotion-of-surgical-masks-antimicrobial-activity-by-disinfection-and-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Benjamin Valdez-Salas,1,2 Ernesto Beltran-Partida,1,2 Nelson Cheng,3 Jorge Salvador-Carlos,2 Ernesto Alonso Valdez-Salas,1 Mario Curiel-Alvarez,2 Roberto Ibarra-Wiley2 1Laboratorio de Biología Molecular y Cáncer, Instituto de Ingeniería, Universidad Autónoma de Baja California, Mexicali, Baja California, Mexico; 2Laboratorio de Corrosión y Materiales Avanzados, Instituto de Ingeniería, Universidad Autónoma de Baja California, Mexicali, Baja California, Mexico; 3Magna International Pte Ltd, SingaporeCorrespondence: Benjamin Valdez-Salas Tel/Fax +526865664154 Ext. 150Email benval@uabc.edu.mxBackground: The COVID-19 pandemic is requesting highly effective protective personnel equipment, mainly for healthcare professionals. However, the current demand has exceeded the supply chain and, consequently, shortage of essential medical materials, such as surgical masks. Due to these alarming limitations, it is crucial to develop effective means of disinfection, reusing, and thereby applying antimicrobial shielding protection to the clinical supplies.Purpose: Therefore, in this work, we developed a novel, economical, and straightforward approach to promote antimicrobial activity to surgical masks by impregnating silver nanoparticles (AgNPs).Methods: Our strategy consisted of fabricating a new alcohol disinfectant formulation combining special surfactants and AgNPs, which is demonstrated to be extensively effective against a broad number of microbial surrogates of SARS-CoV-2.Results: The present nano-formula reported a superior microbial reduction of 99.999% against a wide number of microorganisms. Furthermore, the enveloped H5N1 virus was wholly inactivated after 15 min of disinfection. Far more attractive, the current method for reusing surgical masks did not show outcomes of detrimental amendments, suggesting that the protocol does not alter the filtration effectiveness.Conclusion: The nano-disinfectant provides a valuable strategy for effective decontamination, reuse, and even antimicrobial promotion to surgical masks for frontline clinical personnel.Keywords: surgical mask, antimicrobial, SARS-CoV-2, nanobiotechnology, COVID-19, nanoparticlesValdez-Salas BBeltran-Partida ECheng NSalvador-Carlos JValdez-Salas EACuriel-Alvarez MIbarra-Wiley RDove Medical Pressarticlesurgical maskantimicrobialsars-cov-2nanobiotechnologycovid-19nanoparticlesMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 16, Pp 2689-2702 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	surgical mask antimicrobial sars-cov-2 nanobiotechnology covid-19 nanoparticles Medicine (General) R5-920
spellingShingle	surgical mask antimicrobial sars-cov-2 nanobiotechnology covid-19 nanoparticles Medicine (General) R5-920 Valdez-Salas B Beltran-Partida E Cheng N Salvador-Carlos J Valdez-Salas EA Curiel-Alvarez M Ibarra-Wiley R Promotion of Surgical Masks Antimicrobial Activity by Disinfection and Impregnation with Disinfectant Silver Nanoparticles
description	Benjamin Valdez-Salas,1,2 Ernesto Beltran-Partida,1,2 Nelson Cheng,3 Jorge Salvador-Carlos,2 Ernesto Alonso Valdez-Salas,1 Mario Curiel-Alvarez,2 Roberto Ibarra-Wiley2 1Laboratorio de Biología Molecular y Cáncer, Instituto de Ingeniería, Universidad Autónoma de Baja California, Mexicali, Baja California, Mexico; 2Laboratorio de Corrosión y Materiales Avanzados, Instituto de Ingeniería, Universidad Autónoma de Baja California, Mexicali, Baja California, Mexico; 3Magna International Pte Ltd, SingaporeCorrespondence: Benjamin Valdez-Salas Tel/Fax +526865664154 Ext. 150Email benval@uabc.edu.mxBackground: The COVID-19 pandemic is requesting highly effective protective personnel equipment, mainly for healthcare professionals. However, the current demand has exceeded the supply chain and, consequently, shortage of essential medical materials, such as surgical masks. Due to these alarming limitations, it is crucial to develop effective means of disinfection, reusing, and thereby applying antimicrobial shielding protection to the clinical supplies.Purpose: Therefore, in this work, we developed a novel, economical, and straightforward approach to promote antimicrobial activity to surgical masks by impregnating silver nanoparticles (AgNPs).Methods: Our strategy consisted of fabricating a new alcohol disinfectant formulation combining special surfactants and AgNPs, which is demonstrated to be extensively effective against a broad number of microbial surrogates of SARS-CoV-2.Results: The present nano-formula reported a superior microbial reduction of 99.999% against a wide number of microorganisms. Furthermore, the enveloped H5N1 virus was wholly inactivated after 15 min of disinfection. Far more attractive, the current method for reusing surgical masks did not show outcomes of detrimental amendments, suggesting that the protocol does not alter the filtration effectiveness.Conclusion: The nano-disinfectant provides a valuable strategy for effective decontamination, reuse, and even antimicrobial promotion to surgical masks for frontline clinical personnel.Keywords: surgical mask, antimicrobial, SARS-CoV-2, nanobiotechnology, COVID-19, nanoparticles
format	article
author	Valdez-Salas B Beltran-Partida E Cheng N Salvador-Carlos J Valdez-Salas EA Curiel-Alvarez M Ibarra-Wiley R
author_facet	Valdez-Salas B Beltran-Partida E Cheng N Salvador-Carlos J Valdez-Salas EA Curiel-Alvarez M Ibarra-Wiley R
author_sort	Valdez-Salas B
title	Promotion of Surgical Masks Antimicrobial Activity by Disinfection and Impregnation with Disinfectant Silver Nanoparticles
title_short	Promotion of Surgical Masks Antimicrobial Activity by Disinfection and Impregnation with Disinfectant Silver Nanoparticles
title_full	Promotion of Surgical Masks Antimicrobial Activity by Disinfection and Impregnation with Disinfectant Silver Nanoparticles
title_fullStr	Promotion of Surgical Masks Antimicrobial Activity by Disinfection and Impregnation with Disinfectant Silver Nanoparticles
title_full_unstemmed	Promotion of Surgical Masks Antimicrobial Activity by Disinfection and Impregnation with Disinfectant Silver Nanoparticles
title_sort	promotion of surgical masks antimicrobial activity by disinfection and impregnation with disinfectant silver nanoparticles
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/6f7587f8362f4e4f83d2ebba14ba7ac6
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Promotion of Surgical Masks Antimicrobial Activity by Disinfection and Impregnation with Disinfectant Silver Nanoparticles

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