A comparative chemogenomics strategy to predict potential drug targets in the metazoan pathogen, Schistosoma mansoni.

Schistosomiasis is a prevalent and chronic helmintic disease in tropical regions. Treatment and control relies on chemotherapy with just one drug, praziquantel and this reliance is of concern should clinically relevant drug resistance emerge and spread. Therefore, to identify potential target protei...

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Autores principales: Conor R Caffrey, Andreas Rohwer, Frank Oellien, Richard J Marhöfer, Simon Braschi, Guilherme Oliveira, James H McKerrow, Paul M Selzer
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
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Acceso en línea:https://doaj.org/article/6f89ee6c78bd429a904d5fb89455d660
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