The Role of Inflammation in β-cell Dedifferentiation
Abstract Chronic inflammation impairs insulin secretion and sensitivity. β-cell dedifferentiation has recently been proposed as a mechanism underlying β-cell failure in T2D. Yet the effect of inflammation on β-cell identity in T2D has not been studied. Therefore, we investigated whether pro-inflamma...
Saved in:
Main Authors: | Thierry M. Nordmann, Erez Dror, Friederike Schulze, Shuyang Traub, Ekaterine Berishvili, Charlotte Barbieux, Marianne Böni-Schnetzler, Marc Y. Donath |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
|
Subjects: | |
Online Access: | https://doaj.org/article/6f906ade44424de0a8b12cce0ea33f04 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
IL-1beta promotes the age-associated decline of beta cell function
by: Marianne Böni-Schnetzler, et al.
Published: (2021) -
Dedifferentiation and proliferation of mammalian cardiomyocytes.
by: Yiqiang Zhang, et al.
Published: (2010) -
Integrated exome and RNA sequencing of dedifferentiated liposarcoma
by: Makoto Hirata, et al.
Published: (2019) -
Transient reprogramming of postnatal cardiomyocytes to a dedifferentiated state.
by: Thomas Kisby, et al.
Published: (2021) -
Publisher Correction: Integrated exome and RNA sequencing of dedifferentiated liposarcoma
by: Makoto Hirata, et al.
Published: (2020)