[77] Adult urinary lithiasis and chronic renal insufficiency in 32 cases
Objective: To specify the clinical, metabolic and aetiological characteristics of stone diseases complicated by chronic renal failure. Renal lithiasis is a common, highly recurrent disease that can be complicated by chronic renal failure, which is usually prevented by early diagnosis and adequate me...
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| Autores principales: | , , , , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Taylor & Francis Group
2018
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/6f94ac9f987d4a92bc25ea83eec48acd |
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| Sumario: | Objective: To specify the clinical, metabolic and aetiological characteristics of stone diseases complicated by chronic renal failure. Renal lithiasis is a common, highly recurrent disease that can be complicated by chronic renal failure, which is usually prevented by early diagnosis and adequate medical and surgical management. Methods: Over a 10-year period from 2008 to 2018, we collected 173 patients with a confirmed urolithiasis aetiology, amongst which 32 had chronic renal insufficiency with a creatinine clearance of <60 mL/min at the time of the diagnosis. Results: There were 19 men and 13 women (sex ratio 1.58) with a mean (range) age of 51.59 (32–72) years. The prevalence of renal failure was 18.47%. Two patients had end-stage renal disease. Lithiasis was bilateral in 24 cases and unilateral in eight. In all, 21 patients underwent surgery with nephrectomy in 10, 17 patients had extracorporeal lithotripsy, and four patients had a percutaneous nephrolithotomy. The average time between the onset of lithiasis disease and the aetiological diagnosis was 12 years. In regards to aetiologies we noted: hyperoxaluria in eight cases (primary: five cases, food: three cases), hyperparathyroidism in five cases, a metabolic syndrome in five cases, hyperuricuria in five cases, a lithiasis of infection in six cases (isolated: two cases, associated with a metabolic cause: four cases), cystinuria in two cases, and distal tubular acidosis in one case. Conclusion: The high percentage of chronic renal failure in our patients was the result of late aetiological diagnosis and management. The aggravating factors were infections and nephrectomies. |
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