[77] Adult urinary lithiasis and chronic renal insufficiency in 32 cases

Objective: To specify the clinical, metabolic and aetiological characteristics of stone diseases complicated by chronic renal failure. Renal lithiasis is a common, highly recurrent disease that can be complicated by chronic renal failure, which is usually prevented by early diagnosis and adequate me...

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Autores principales: Hayet Kaaroud, Asma Bettaieb, Nutritioniste Hanene Kharroubi, Hiba Ghabi, Taieb Ben Abdallah, Athi Ben Hamida, Mna Talbi, Hanene Baccouche, Olfa Marrakchi, Kahna Bouzidi, Haroun Ayed, Mohamed Cherif, Mohamed Chebil
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Publicado: Taylor & Francis Group 2018
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spelling oai:doaj.org-article:6f94ac9f987d4a92bc25ea83eec48acd2021-12-02T10:12:19Z[77] Adult urinary lithiasis and chronic renal insufficiency in 32 cases2090-598X10.1016/j.aju.2018.10.030https://doaj.org/article/6f94ac9f987d4a92bc25ea83eec48acd2018-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2090598X18301244https://doaj.org/toc/2090-598XObjective: To specify the clinical, metabolic and aetiological characteristics of stone diseases complicated by chronic renal failure. Renal lithiasis is a common, highly recurrent disease that can be complicated by chronic renal failure, which is usually prevented by early diagnosis and adequate medical and surgical management. Methods: Over a 10-year period from 2008 to 2018, we collected 173 patients with a confirmed urolithiasis aetiology, amongst which 32 had chronic renal insufficiency with a creatinine clearance of <60 mL/min at the time of the diagnosis. Results: There were 19 men and 13 women (sex ratio 1.58) with a mean (range) age of 51.59 (32–72) years. The prevalence of renal failure was 18.47%. Two patients had end-stage renal disease. Lithiasis was bilateral in 24 cases and unilateral in eight. In all, 21 patients underwent surgery with nephrectomy in 10, 17 patients had extracorporeal lithotripsy, and four patients had a percutaneous nephrolithotomy. The average time between the onset of lithiasis disease and the aetiological diagnosis was 12 years. In regards to aetiologies we noted: hyperoxaluria in eight cases (primary: five cases, food: three cases), hyperparathyroidism in five cases, a metabolic syndrome in five cases, hyperuricuria in five cases, a lithiasis of infection in six cases (isolated: two cases, associated with a metabolic cause: four cases), cystinuria in two cases, and distal tubular acidosis in one case. Conclusion: The high percentage of chronic renal failure in our patients was the result of late aetiological diagnosis and management. The aggravating factors were infections and nephrectomies.Hayet KaaroudAsma BettaiebNutritioniste Hanene KharroubiHiba GhabiTaieb Ben AbdallahAthi Ben HamidaMna TalbiHanene BaccoucheOlfa MarrakchiKahna BouzidiHaroun AyedMohamed CherifMohamed ChebilTaylor & Francis GrouparticleDiseases of the genitourinary system. UrologyRC870-923ENArab Journal of Urology, Vol 16, Iss , Pp S36- (2018)
institution DOAJ
collection DOAJ
language EN
topic Diseases of the genitourinary system. Urology
RC870-923
spellingShingle Diseases of the genitourinary system. Urology
RC870-923
Hayet Kaaroud
Asma Bettaieb
Nutritioniste Hanene Kharroubi
Hiba Ghabi
Taieb Ben Abdallah
Athi Ben Hamida
Mna Talbi
Hanene Baccouche
Olfa Marrakchi
Kahna Bouzidi
Haroun Ayed
Mohamed Cherif
Mohamed Chebil
[77] Adult urinary lithiasis and chronic renal insufficiency in 32 cases
description Objective: To specify the clinical, metabolic and aetiological characteristics of stone diseases complicated by chronic renal failure. Renal lithiasis is a common, highly recurrent disease that can be complicated by chronic renal failure, which is usually prevented by early diagnosis and adequate medical and surgical management. Methods: Over a 10-year period from 2008 to 2018, we collected 173 patients with a confirmed urolithiasis aetiology, amongst which 32 had chronic renal insufficiency with a creatinine clearance of <60 mL/min at the time of the diagnosis. Results: There were 19 men and 13 women (sex ratio 1.58) with a mean (range) age of 51.59 (32–72) years. The prevalence of renal failure was 18.47%. Two patients had end-stage renal disease. Lithiasis was bilateral in 24 cases and unilateral in eight. In all, 21 patients underwent surgery with nephrectomy in 10, 17 patients had extracorporeal lithotripsy, and four patients had a percutaneous nephrolithotomy. The average time between the onset of lithiasis disease and the aetiological diagnosis was 12 years. In regards to aetiologies we noted: hyperoxaluria in eight cases (primary: five cases, food: three cases), hyperparathyroidism in five cases, a metabolic syndrome in five cases, hyperuricuria in five cases, a lithiasis of infection in six cases (isolated: two cases, associated with a metabolic cause: four cases), cystinuria in two cases, and distal tubular acidosis in one case. Conclusion: The high percentage of chronic renal failure in our patients was the result of late aetiological diagnosis and management. The aggravating factors were infections and nephrectomies.
format article
author Hayet Kaaroud
Asma Bettaieb
Nutritioniste Hanene Kharroubi
Hiba Ghabi
Taieb Ben Abdallah
Athi Ben Hamida
Mna Talbi
Hanene Baccouche
Olfa Marrakchi
Kahna Bouzidi
Haroun Ayed
Mohamed Cherif
Mohamed Chebil
author_facet Hayet Kaaroud
Asma Bettaieb
Nutritioniste Hanene Kharroubi
Hiba Ghabi
Taieb Ben Abdallah
Athi Ben Hamida
Mna Talbi
Hanene Baccouche
Olfa Marrakchi
Kahna Bouzidi
Haroun Ayed
Mohamed Cherif
Mohamed Chebil
author_sort Hayet Kaaroud
title [77] Adult urinary lithiasis and chronic renal insufficiency in 32 cases
title_short [77] Adult urinary lithiasis and chronic renal insufficiency in 32 cases
title_full [77] Adult urinary lithiasis and chronic renal insufficiency in 32 cases
title_fullStr [77] Adult urinary lithiasis and chronic renal insufficiency in 32 cases
title_full_unstemmed [77] Adult urinary lithiasis and chronic renal insufficiency in 32 cases
title_sort [77] adult urinary lithiasis and chronic renal insufficiency in 32 cases
publisher Taylor & Francis Group
publishDate 2018
url https://doaj.org/article/6f94ac9f987d4a92bc25ea83eec48acd
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