Preventing tissue fibrosis by local biomaterials interfacing of specific cryptic extracellular matrix information
Matrix metalloproteinase enzymes are widely known to contribute to the breakdown of tissues. Here, the authors utilise a biomaterial substrate functionalised with a laminin fragment to modulate the expression of these enzymes, subsequently controlling the integrity of tissue.
Guardado en:
Autores principales: | Christine-Maria Horejs, Jean-Philippe St-Pierre, Juha R. M. Ojala, Joseph A. M. Steele, Patricia Barros da Silva, Angela Rynne-Vidal, Stephanie A. Maynard, Catherine S. Hansel, Clara Rodríguez-Fernández, Manuel M. Mazo, Amanda Y. F. You, Alex J. Wang, Thomas von Erlach, Karl Tryggvason, Manuel López-Cabrera, Molly M. Stevens |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/6f96d69568c34d5fb8957a8cd8f04a9a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Extracellular Matrix-Based Biomaterials for Cardiovascular Tissue Engineering
por: Astha Khanna, et al.
Publicado: (2021) -
Cell-derived Extracellular Matrix as maintaining Biomaterial for adipogenic differentiation
por: Kluger Petra J., et al.
Publicado: (2020) -
Matching the Cellulose/Silica Films Surface Properties for Design of Biomaterials That Modulate Extracellular Matrix
por: Adina-Maria Dobos, et al.
Publicado: (2021) -
Quantitative volumetric Raman imaging of three dimensional cell cultures
por: Charalambos Kallepitis, et al.
Publicado: (2017) -
Evaluation of Decellularized Matrix and ß-Tricalcium Phosphate as Biomaterials for Bone Neoformation: In vivo Study
por: Muñoz-Ruíz,Abraham, et al.
Publicado: (2017)