Increasing the reproducibility of fluid biomarker studies in neurodegenerative studies

Many fluid biomarker findings have had low reproducibility despite initially promising results. Here, the authors review possible sources for low reproducibility of studies on fluid biomarkers for neurodegenerative diseases and suggest guidelines for the biomarker community to agree on and implement...

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Autores principales: Niklas Mattsson-Carlgren, Sebastian Palmqvist, Kaj Blennow, Oskar Hansson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/6f9ad7fe719b463fa1f77344a46120a2
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spelling oai:doaj.org-article:6f9ad7fe719b463fa1f77344a46120a22021-12-02T13:24:16ZIncreasing the reproducibility of fluid biomarker studies in neurodegenerative studies10.1038/s41467-020-19957-62041-1723https://doaj.org/article/6f9ad7fe719b463fa1f77344a46120a22020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19957-6https://doaj.org/toc/2041-1723Many fluid biomarker findings have had low reproducibility despite initially promising results. Here, the authors review possible sources for low reproducibility of studies on fluid biomarkers for neurodegenerative diseases and suggest guidelines for the biomarker community to agree on and implement.Niklas Mattsson-CarlgrenSebastian PalmqvistKaj BlennowOskar HanssonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Niklas Mattsson-Carlgren
Sebastian Palmqvist
Kaj Blennow
Oskar Hansson
Increasing the reproducibility of fluid biomarker studies in neurodegenerative studies
description Many fluid biomarker findings have had low reproducibility despite initially promising results. Here, the authors review possible sources for low reproducibility of studies on fluid biomarkers for neurodegenerative diseases and suggest guidelines for the biomarker community to agree on and implement.
format article
author Niklas Mattsson-Carlgren
Sebastian Palmqvist
Kaj Blennow
Oskar Hansson
author_facet Niklas Mattsson-Carlgren
Sebastian Palmqvist
Kaj Blennow
Oskar Hansson
author_sort Niklas Mattsson-Carlgren
title Increasing the reproducibility of fluid biomarker studies in neurodegenerative studies
title_short Increasing the reproducibility of fluid biomarker studies in neurodegenerative studies
title_full Increasing the reproducibility of fluid biomarker studies in neurodegenerative studies
title_fullStr Increasing the reproducibility of fluid biomarker studies in neurodegenerative studies
title_full_unstemmed Increasing the reproducibility of fluid biomarker studies in neurodegenerative studies
title_sort increasing the reproducibility of fluid biomarker studies in neurodegenerative studies
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/6f9ad7fe719b463fa1f77344a46120a2
work_keys_str_mv AT niklasmattssoncarlgren increasingthereproducibilityoffluidbiomarkerstudiesinneurodegenerativestudies
AT sebastianpalmqvist increasingthereproducibilityoffluidbiomarkerstudiesinneurodegenerativestudies
AT kajblennow increasingthereproducibilityoffluidbiomarkerstudiesinneurodegenerativestudies
AT oskarhansson increasingthereproducibilityoffluidbiomarkerstudiesinneurodegenerativestudies
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