Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection
Ya-Lang Huang et al. report a mechanism for TLR3-mediated signaling after immune simulation and influenza virus infection by way of the co-receptor CLEC18A. This study found that a single amino acid change in CLEC18A(S339R) can enhance the production of type I and type III interferons to suppress vi...
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Autores principales: | Ya-Lang Huang, Ming-Ting Huang, Pei-Shan Sung, Teh-Ying Chou, Ruey-Bing Yang, An-Suei Yang, Chung-Ming Yu, Yu-Wen Hsu, Wei-Chiao Chang, Shie-Liang Hsieh |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/6fa2f4a4e45c413fa7b217a06e675fd7 |
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