Early priming minimizes the age-related immune compromise of CD8⁺ T cell diversity and function.

Early priming minimizes the age-related immune compromise of CD8⁺ T cell diversity and function.

The elderly are particularly susceptible to influenza A virus infections, with increased occurrence, disease severity and reduced vaccine efficacy attributed to declining immunity. Experimentally, the age-dependent decline in influenza-specific CD8(+) T cell responsiveness reflects both functional c...

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Detalles Bibliográficos
Autores principales: Sophie A Valkenburg, Vanessa Venturi, Thurston H Y Dang, Nicola L Bird, Peter C Doherty, Stephen J Turner, Miles P Davenport, Katherine Kedzierska
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/6fa5a2ce4ae94b5194f76687d579ccd1
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