Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue

Functionalizing antimicrobial peptides with fluorescent groups is a useful strategy for imaging infection, but the tag can alter the performance of the probe. Here, the authors report a spacer-free method to directly functionalise an amino acid with a fluorogenic group and prepare peptide-based imag...

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Autores principales:	Lorena Mendive-Tapia, Can Zhao, Ahsan R. Akram, Sara Preciado, Fernando Albericio, Martin Lee, Alan Serrels, Nicola Kielland, Nick D Read, Rodolfo Lavilla, Marc Vendrell
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6fb748ca547d4e038602fff23bee1fb9
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spelling	oai:doaj.org-article:6fb748ca547d4e038602fff23bee1fb92021-12-02T17:31:34ZSpacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue10.1038/ncomms109402041-1723https://doaj.org/article/6fb748ca547d4e038602fff23bee1fb92016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10940https://doaj.org/toc/2041-1723Functionalizing antimicrobial peptides with fluorescent groups is a useful strategy for imaging infection, but the tag can alter the performance of the probe. Here, the authors report a spacer-free method to directly functionalise an amino acid with a fluorogenic group and prepare peptide-based imaging agents for fungal infection.Lorena Mendive-TapiaCan ZhaoAhsan R. AkramSara PreciadoFernando AlbericioMartin LeeAlan SerrelsNicola KiellandNick D ReadRodolfo LavillaMarc VendrellNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lorena Mendive-Tapia Can Zhao Ahsan R. Akram Sara Preciado Fernando Albericio Martin Lee Alan Serrels Nicola Kielland Nick D Read Rodolfo Lavilla Marc Vendrell Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue
description	Functionalizing antimicrobial peptides with fluorescent groups is a useful strategy for imaging infection, but the tag can alter the performance of the probe. Here, the authors report a spacer-free method to directly functionalise an amino acid with a fluorogenic group and prepare peptide-based imaging agents for fungal infection.
format	article
author	Lorena Mendive-Tapia Can Zhao Ahsan R. Akram Sara Preciado Fernando Albericio Martin Lee Alan Serrels Nicola Kielland Nick D Read Rodolfo Lavilla Marc Vendrell
author_facet	Lorena Mendive-Tapia Can Zhao Ahsan R. Akram Sara Preciado Fernando Albericio Martin Lee Alan Serrels Nicola Kielland Nick D Read Rodolfo Lavilla Marc Vendrell
author_sort	Lorena Mendive-Tapia
title	Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue
title_short	Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue
title_full	Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue
title_fullStr	Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue
title_full_unstemmed	Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue
title_sort	spacer-free bodipy fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/6fb748ca547d4e038602fff23bee1fb9
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Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue

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