Control of diabetic hyperglycaemia and insulin resistance through TSC22D4

TSC22D4 regulates hepatic lipoprotein production, but has so far mainly been studied in the context of cancer cachexia. Here, the authors show TSC22D4 inhibition improves insulin sensitivity in several mouse models of diabetes, which they attribute at least in part to the induction of secreted LCN13...

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Autores principales:	Bilgen Ekim Üstünel, Kilian Friedrich, Adriano Maida, Xiaoyue Wang, Anja Krones-Herzig, Oksana Seibert, Anke Sommerfeld, Allan Jones, Tjeerd P. Sijmonsma, Carsten Sticht, Norbert Gretz, Thomas Fleming, Peter P. Nawroth, Wolfgang Stremmel, Adam J. Rose, Mauricio Berriel-Diaz, Matthias Blüher, Stephan Herzig
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6fbad84b0b124d8487619a25d73053a2
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spelling	oai:doaj.org-article:6fbad84b0b124d8487619a25d73053a22021-12-02T17:33:20ZControl of diabetic hyperglycaemia and insulin resistance through TSC22D410.1038/ncomms132672041-1723https://doaj.org/article/6fbad84b0b124d8487619a25d73053a22016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13267https://doaj.org/toc/2041-1723TSC22D4 regulates hepatic lipoprotein production, but has so far mainly been studied in the context of cancer cachexia. Here, the authors show TSC22D4 inhibition improves insulin sensitivity in several mouse models of diabetes, which they attribute at least in part to the induction of secreted LCN13.Bilgen Ekim ÜstünelKilian FriedrichAdriano MaidaXiaoyue WangAnja Krones-HerzigOksana SeibertAnke SommerfeldAllan JonesTjeerd P. SijmonsmaCarsten StichtNorbert GretzThomas FlemingPeter P. NawrothWolfgang StremmelAdam J. RoseMauricio Berriel-DiazMatthias BlüherStephan HerzigNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bilgen Ekim Üstünel Kilian Friedrich Adriano Maida Xiaoyue Wang Anja Krones-Herzig Oksana Seibert Anke Sommerfeld Allan Jones Tjeerd P. Sijmonsma Carsten Sticht Norbert Gretz Thomas Fleming Peter P. Nawroth Wolfgang Stremmel Adam J. Rose Mauricio Berriel-Diaz Matthias Blüher Stephan Herzig Control of diabetic hyperglycaemia and insulin resistance through TSC22D4
description	TSC22D4 regulates hepatic lipoprotein production, but has so far mainly been studied in the context of cancer cachexia. Here, the authors show TSC22D4 inhibition improves insulin sensitivity in several mouse models of diabetes, which they attribute at least in part to the induction of secreted LCN13.
format	article
author	Bilgen Ekim Üstünel Kilian Friedrich Adriano Maida Xiaoyue Wang Anja Krones-Herzig Oksana Seibert Anke Sommerfeld Allan Jones Tjeerd P. Sijmonsma Carsten Sticht Norbert Gretz Thomas Fleming Peter P. Nawroth Wolfgang Stremmel Adam J. Rose Mauricio Berriel-Diaz Matthias Blüher Stephan Herzig
author_facet	Bilgen Ekim Üstünel Kilian Friedrich Adriano Maida Xiaoyue Wang Anja Krones-Herzig Oksana Seibert Anke Sommerfeld Allan Jones Tjeerd P. Sijmonsma Carsten Sticht Norbert Gretz Thomas Fleming Peter P. Nawroth Wolfgang Stremmel Adam J. Rose Mauricio Berriel-Diaz Matthias Blüher Stephan Herzig
author_sort	Bilgen Ekim Üstünel
title	Control of diabetic hyperglycaemia and insulin resistance through TSC22D4
title_short	Control of diabetic hyperglycaemia and insulin resistance through TSC22D4
title_full	Control of diabetic hyperglycaemia and insulin resistance through TSC22D4
title_fullStr	Control of diabetic hyperglycaemia and insulin resistance through TSC22D4
title_full_unstemmed	Control of diabetic hyperglycaemia and insulin resistance through TSC22D4
title_sort	control of diabetic hyperglycaemia and insulin resistance through tsc22d4
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/6fbad84b0b124d8487619a25d73053a2
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Control of diabetic hyperglycaemia and insulin resistance through TSC22D4

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