Control of diabetic hyperglycaemia and insulin resistance through TSC22D4
TSC22D4 regulates hepatic lipoprotein production, but has so far mainly been studied in the context of cancer cachexia. Here, the authors show TSC22D4 inhibition improves insulin sensitivity in several mouse models of diabetes, which they attribute at least in part to the induction of secreted LCN13...
Guardado en:
Autores principales: | Bilgen Ekim Üstünel, Kilian Friedrich, Adriano Maida, Xiaoyue Wang, Anja Krones-Herzig, Oksana Seibert, Anke Sommerfeld, Allan Jones, Tjeerd P. Sijmonsma, Carsten Sticht, Norbert Gretz, Thomas Fleming, Peter P. Nawroth, Wolfgang Stremmel, Adam J. Rose, Mauricio Berriel-Diaz, Matthias Blüher, Stephan Herzig |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
|
Materias: | |
Acceso en línea: | https://doaj.org/article/6fbad84b0b124d8487619a25d73053a2 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Hyperglycaemia in criticaly ill patients
por: Tatiana Valer'evna Klypa, et al.
Publicado: (2015) -
Diabetic Pneumopathy–A New Diabetes-Associated Complication: Mechanisms, Consequences and Treatment Considerations
por: Stefan Kopf, et al.
Publicado: (2021) -
Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells
por: Melissa F. Brereton, et al.
Publicado: (2016) -
Valproic acid influences the expression of genes implicated with hyperglycaemia-induced complement and coagulation pathways
por: Marina Barreto Felisbino, et al.
Publicado: (2021) -
Detection of TSC1/TSC2 mosaic variants in patients with cardiac rhabdomyoma and tuberous sclerosis complex by hybrid‐capture next‐generation sequencing
por: Siyu Wang, et al.
Publicado: (2021)