In silico experimentation of glioma microenvironment development and anti-tumor therapy.
Tumor cells do not develop in isolation, but co-evolve with stromal cells and tumor-associated immune cells in a tumor microenvironment mediated by an array of soluble factors, forming a complex intercellular signaling network. Herein, we report an unbiased, generic model to integrate prior biochemi...
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Auteurs principaux: | Yu Wu, Yao Lu, Weiqiang Chen, Jianping Fu, Rong Fan |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2012
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Accès en ligne: | https://doaj.org/article/6fbc65b57a2a4a96994dc4b67ec1afc4 |
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