Halo-fluorescein for photodynamic bacteria inactivation in extremely acidic conditions

Photodynamic inactivation is a common antibacterial method but often fails in extremely acidic environments (pH< 4). Here, the authors demonstrate halogenation of fluorescein for the development of a photodynamic agent which works in extremely acidic environments and demonstrate sterilisation app...

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Bibliographic Details
Main Authors: Ying Wang, Jiazhuo Li, Zhiwei Zhou, Ronghui Zhou, Qun Sun, Peng Wu
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/6fc4bd95f41d4d4db8c3d2ccd0267407
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Summary:Photodynamic inactivation is a common antibacterial method but often fails in extremely acidic environments (pH< 4). Here, the authors demonstrate halogenation of fluorescein for the development of a photodynamic agent which works in extremely acidic environments and demonstrate sterilisation applications in fruit juice and in vivo.