Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function

Mesenchymal stromal cells drive renal regeneration following injury. Here, the authors show that human mesenchymal stromal cells, when transplanted into mice with acute kidney injury, stimulate renal tubular cell growth and enhance mitochondrial function via SIRT3.

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Auteurs principaux:	Luca Perico, Marina Morigi, Cinzia Rota, Matteo Breno, Caterina Mele, Marina Noris, Martino Introna, Chiara Capelli, Lorena Longaretti, Daniela Rottoli, Sara Conti, Daniela Corna, Giuseppe Remuzzi, Ariela Benigni
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2017
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/6fc8f02e7cff48b38a9bfd1b8f67f44c
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spelling	oai:doaj.org-article:6fc8f02e7cff48b38a9bfd1b8f67f44c2021-12-02T15:39:00ZHuman mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function10.1038/s41467-017-00937-22041-1723https://doaj.org/article/6fc8f02e7cff48b38a9bfd1b8f67f44c2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00937-2https://doaj.org/toc/2041-1723Mesenchymal stromal cells drive renal regeneration following injury. Here, the authors show that human mesenchymal stromal cells, when transplanted into mice with acute kidney injury, stimulate renal tubular cell growth and enhance mitochondrial function via SIRT3.Luca PericoMarina MorigiCinzia RotaMatteo BrenoCaterina MeleMarina NorisMartino IntronaChiara CapelliLorena LongarettiDaniela RottoliSara ContiDaniela CornaGiuseppe RemuzziAriela BenigniNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Luca Perico Marina Morigi Cinzia Rota Matteo Breno Caterina Mele Marina Noris Martino Introna Chiara Capelli Lorena Longaretti Daniela Rottoli Sara Conti Daniela Corna Giuseppe Remuzzi Ariela Benigni Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function
description	Mesenchymal stromal cells drive renal regeneration following injury. Here, the authors show that human mesenchymal stromal cells, when transplanted into mice with acute kidney injury, stimulate renal tubular cell growth and enhance mitochondrial function via SIRT3.
format	article
author	Luca Perico Marina Morigi Cinzia Rota Matteo Breno Caterina Mele Marina Noris Martino Introna Chiara Capelli Lorena Longaretti Daniela Rottoli Sara Conti Daniela Corna Giuseppe Remuzzi Ariela Benigni
author_facet	Luca Perico Marina Morigi Cinzia Rota Matteo Breno Caterina Mele Marina Noris Martino Introna Chiara Capelli Lorena Longaretti Daniela Rottoli Sara Conti Daniela Corna Giuseppe Remuzzi Ariela Benigni
author_sort	Luca Perico
title	Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function
title_short	Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function
title_full	Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function
title_fullStr	Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function
title_full_unstemmed	Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function
title_sort	human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/6fc8f02e7cff48b38a9bfd1b8f67f44c
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Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function

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