Impact of extreme (flat and steep) keratometry on the safety and efficacy of small incision lenticule extraction (SMILE)

Abstract Little is known about the connection between preoperative keratometry and postoperative results of myopic small-incision lenticule extraction (SMILE). To determine the influence of extreme (flat and steep) corneal keratometry on the safety and efficacy of SMILE, the databases of the Departm...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Nikolaus Luft, Jakob Siedlecki, Franziska Reinking, Wolfgang J. Mayer, Benedikt Schworm, Stefan Kassumeh, Siegfried G. Priglinger, Martin Dirisamer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6fc9535b8ef146efb6492860d1739d98
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6fc9535b8ef146efb6492860d1739d98
record_format	dspace
spelling	oai:doaj.org-article:6fc9535b8ef146efb6492860d1739d982021-12-02T17:19:16ZImpact of extreme (flat and steep) keratometry on the safety and efficacy of small incision lenticule extraction (SMILE)10.1038/s41598-021-97375-42045-2322https://doaj.org/article/6fc9535b8ef146efb6492860d1739d982021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-97375-4https://doaj.org/toc/2045-2322Abstract Little is known about the connection between preoperative keratometry and postoperative results of myopic small-incision lenticule extraction (SMILE). To determine the influence of extreme (flat and steep) corneal keratometry on the safety and efficacy of SMILE, the databases of the Department of Ophthalmology, Ludwig-Maximilians-University Munich, Germany, and SMILE Eyes Linz, Austria, were screened for patients with steep and flat keratometry who had undergone SMILE. In this cross-sectional matched comparative cohort study, eyes with markedly flat (< 42.0 diopters; D) or steep (≥ 47.0D) preoperative corneal keratometry were matched to a cohort of eyes with regular keratometry (42.0–46.9D) by preoperative manifest refractive spherical equivalent and cylinder, age, corrected distance visual acuity and surgical SMILE parameters. The standardized graphs and terms for refractive surgery results were applied to compare the three groups. Changes in higher order aberrations (HOAs) were evaluated on Scheimpflug imaging. In total, 63 eyes (21 each) of 54 patients with a mean refractive spherical equivalent of − 5.21 ± 1.59 D were followed up for a mean of 9.2 ± 6.1 (minimum ≥ 3) months. Mean baseline keratometry was 41.3 ± 0.7D (flat), 45.5 ± 1.0D (regular) and 47.7 ± 0.6D (steep) (p < 0.0001). Compared to the regular group, the flat and the steep cornea group resulted in a non-inferior percentage of eyes within ± 0.50 D of target refraction (p = 0.20), uncorrected distance visual acuity (p = 0.95) and corrected distance visual acuity (p = 0.20). Flat corneas however experienced a stronger induction of spherical aberration (SA) compared to the steep group (p = 0.0005). In conclusion, non-inferior outcomes of SMILE can also be expected in eyes with steep (≥ 47D) or flat (< 42D) preoperative keratometry, while SMILE however induces more SA in eyes with a flat keratometry.Nikolaus LuftJakob SiedleckiFranziska ReinkingWolfgang J. MayerBenedikt SchwormStefan KassumehSiegfried G. PriglingerMartin DirisamerNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Nikolaus Luft Jakob Siedlecki Franziska Reinking Wolfgang J. Mayer Benedikt Schworm Stefan Kassumeh Siegfried G. Priglinger Martin Dirisamer Impact of extreme (flat and steep) keratometry on the safety and efficacy of small incision lenticule extraction (SMILE)
description	Abstract Little is known about the connection between preoperative keratometry and postoperative results of myopic small-incision lenticule extraction (SMILE). To determine the influence of extreme (flat and steep) corneal keratometry on the safety and efficacy of SMILE, the databases of the Department of Ophthalmology, Ludwig-Maximilians-University Munich, Germany, and SMILE Eyes Linz, Austria, were screened for patients with steep and flat keratometry who had undergone SMILE. In this cross-sectional matched comparative cohort study, eyes with markedly flat (< 42.0 diopters; D) or steep (≥ 47.0D) preoperative corneal keratometry were matched to a cohort of eyes with regular keratometry (42.0–46.9D) by preoperative manifest refractive spherical equivalent and cylinder, age, corrected distance visual acuity and surgical SMILE parameters. The standardized graphs and terms for refractive surgery results were applied to compare the three groups. Changes in higher order aberrations (HOAs) were evaluated on Scheimpflug imaging. In total, 63 eyes (21 each) of 54 patients with a mean refractive spherical equivalent of − 5.21 ± 1.59 D were followed up for a mean of 9.2 ± 6.1 (minimum ≥ 3) months. Mean baseline keratometry was 41.3 ± 0.7D (flat), 45.5 ± 1.0D (regular) and 47.7 ± 0.6D (steep) (p < 0.0001). Compared to the regular group, the flat and the steep cornea group resulted in a non-inferior percentage of eyes within ± 0.50 D of target refraction (p = 0.20), uncorrected distance visual acuity (p = 0.95) and corrected distance visual acuity (p = 0.20). Flat corneas however experienced a stronger induction of spherical aberration (SA) compared to the steep group (p = 0.0005). In conclusion, non-inferior outcomes of SMILE can also be expected in eyes with steep (≥ 47D) or flat (< 42D) preoperative keratometry, while SMILE however induces more SA in eyes with a flat keratometry.
format	article
author	Nikolaus Luft Jakob Siedlecki Franziska Reinking Wolfgang J. Mayer Benedikt Schworm Stefan Kassumeh Siegfried G. Priglinger Martin Dirisamer
author_facet	Nikolaus Luft Jakob Siedlecki Franziska Reinking Wolfgang J. Mayer Benedikt Schworm Stefan Kassumeh Siegfried G. Priglinger Martin Dirisamer
author_sort	Nikolaus Luft
title	Impact of extreme (flat and steep) keratometry on the safety and efficacy of small incision lenticule extraction (SMILE)
title_short	Impact of extreme (flat and steep) keratometry on the safety and efficacy of small incision lenticule extraction (SMILE)
title_full	Impact of extreme (flat and steep) keratometry on the safety and efficacy of small incision lenticule extraction (SMILE)
title_fullStr	Impact of extreme (flat and steep) keratometry on the safety and efficacy of small incision lenticule extraction (SMILE)
title_full_unstemmed	Impact of extreme (flat and steep) keratometry on the safety and efficacy of small incision lenticule extraction (SMILE)
title_sort	impact of extreme (flat and steep) keratometry on the safety and efficacy of small incision lenticule extraction (smile)
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6fc9535b8ef146efb6492860d1739d98
work_keys_str_mv	AT nikolausluft impactofextremeflatandsteepkeratometryonthesafetyandefficacyofsmallincisionlenticuleextractionsmile AT jakobsiedlecki impactofextremeflatandsteepkeratometryonthesafetyandefficacyofsmallincisionlenticuleextractionsmile AT franziskareinking impactofextremeflatandsteepkeratometryonthesafetyandefficacyofsmallincisionlenticuleextractionsmile AT wolfgangjmayer impactofextremeflatandsteepkeratometryonthesafetyandefficacyofsmallincisionlenticuleextractionsmile AT benediktschworm impactofextremeflatandsteepkeratometryonthesafetyandefficacyofsmallincisionlenticuleextractionsmile AT stefankassumeh impactofextremeflatandsteepkeratometryonthesafetyandefficacyofsmallincisionlenticuleextractionsmile AT siegfriedgpriglinger impactofextremeflatandsteepkeratometryonthesafetyandefficacyofsmallincisionlenticuleextractionsmile AT martindirisamer impactofextremeflatandsteepkeratometryonthesafetyandefficacyofsmallincisionlenticuleextractionsmile
_version_	1718381031874101248

Impact of extreme (flat and steep) keratometry on the safety and efficacy of small incision lenticule extraction (SMILE)

Ejemplares similares