HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway

MHC class I and II molecules generally present endogenous and exogenous peptides, respectively, through distinct mechanisms. Here, the authors show that the class II molecule HLA-DP84Glyuses both class I and II mechanisms to constitutively present peptides.

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Autores principales:	Yuki Yamashita, Mark Anczurowski, Munehide Nakatsugawa, Makito Tanaka, Yuki Kagoya, Ankit Sinha, Kenji Chamoto, Toshiki Ochi, Tingxi Guo, Kayoko Saso, Marcus O. Butler, Mark D. Minden, Thomas Kislinger, Naoto Hirano
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6fca40eaed414738a7794321edcd0a22
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spelling	oai:doaj.org-article:6fca40eaed414738a7794321edcd0a222021-12-02T14:41:07ZHLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway10.1038/ncomms152442041-1723https://doaj.org/article/6fca40eaed414738a7794321edcd0a222017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15244https://doaj.org/toc/2041-1723MHC class I and II molecules generally present endogenous and exogenous peptides, respectively, through distinct mechanisms. Here, the authors show that the class II molecule HLA-DP84Glyuses both class I and II mechanisms to constitutively present peptides.Yuki YamashitaMark AnczurowskiMunehide NakatsugawaMakito TanakaYuki KagoyaAnkit SinhaKenji ChamotoToshiki OchiTingxi GuoKayoko SasoMarcus O. ButlerMark D. MindenThomas KislingerNaoto HiranoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuki Yamashita Mark Anczurowski Munehide Nakatsugawa Makito Tanaka Yuki Kagoya Ankit Sinha Kenji Chamoto Toshiki Ochi Tingxi Guo Kayoko Saso Marcus O. Butler Mark D. Minden Thomas Kislinger Naoto Hirano HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway
description	MHC class I and II molecules generally present endogenous and exogenous peptides, respectively, through distinct mechanisms. Here, the authors show that the class II molecule HLA-DP84Glyuses both class I and II mechanisms to constitutively present peptides.
format	article
author	Yuki Yamashita Mark Anczurowski Munehide Nakatsugawa Makito Tanaka Yuki Kagoya Ankit Sinha Kenji Chamoto Toshiki Ochi Tingxi Guo Kayoko Saso Marcus O. Butler Mark D. Minden Thomas Kislinger Naoto Hirano
author_facet	Yuki Yamashita Mark Anczurowski Munehide Nakatsugawa Makito Tanaka Yuki Kagoya Ankit Sinha Kenji Chamoto Toshiki Ochi Tingxi Guo Kayoko Saso Marcus O. Butler Mark D. Minden Thomas Kislinger Naoto Hirano
author_sort	Yuki Yamashita
title	HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway
title_short	HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway
title_full	HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway
title_fullStr	HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway
title_full_unstemmed	HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway
title_sort	hla-dp84gly constitutively presents endogenous peptides generated by the class i antigen processing pathway
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/6fca40eaed414738a7794321edcd0a22
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HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway

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