Construction of a Nano-Controlled Release Methotrexate Delivery System for the Treatment of Rheumatoid Arthritis by Local Percutaneous Administration

A drug delivery system was specifically designed for the treatment of rheumatoid arthritis (RA) by local percutaneous administration and the nano-controlled release of methotrexate (MTX). The release behavior of MTX from the synthesized MTX-mSiO<sub>2</sub>@PDA system was investigated in...

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Autores principales: Tingting Guo, Xu Kang, Sifan Ren, Xianjin Ouyang, Mingming Chang
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/6fcdfd0277584f1dad57dd24216c4a7d
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