Identification of clusters of rapid and slow decliners among subjects at risk for Alzheimer’s disease

Identification of clusters of rapid and slow decliners among subjects at risk for Alzheimer’s disease

Abstract The heterogeneity of Alzheimer’s disease contributes to the high failure rate of prior clinical trials. We analyzed 5-year longitudinal outcomes and biomarker data from 562 subjects with mild cognitive impairment (MCI) from two national studies (ADNI) using a novel multilayer clustering alg...

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Autores principales: Dragan Gamberger, Nada Lavrač, Shantanu Srivatsa, Rudolph E. Tanzi, P. Murali Doraiswamy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/6fce1100c1324e30be2bdb1cd214408a
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