A comprehensive map of alternative polyadenylation in African American and European American lung cancer patients

Alternative polyadenylation (APA) regulates the length of the 3′UTR of mRNA. Here, the authors describe a method to accurately measure APA in tumours and apply this method to investigate the differences in APA in African American and European American lung cancer samples.

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Autores principales:	Adriana Zingone, Sanju Sinha, Michael Ante, Cu Nguyen, Dalia Daujotyte, Elise D. Bowman, Neelam Sinha, Khadijah A. Mitchell, Qingrong Chen, Chunhua Yan, Phillipe Loher, Daoud Meerzaman, Eytan Ruppin, Bríd M. Ryan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6fd436d5357e43f98a5a57bc9ef4218b
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spelling	oai:doaj.org-article:6fd436d5357e43f98a5a57bc9ef4218b2021-12-02T15:15:05ZA comprehensive map of alternative polyadenylation in African American and European American lung cancer patients10.1038/s41467-021-25763-52041-1723https://doaj.org/article/6fd436d5357e43f98a5a57bc9ef4218b2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25763-5https://doaj.org/toc/2041-1723Alternative polyadenylation (APA) regulates the length of the 3′UTR of mRNA. Here, the authors describe a method to accurately measure APA in tumours and apply this method to investigate the differences in APA in African American and European American lung cancer samples.Adriana ZingoneSanju SinhaMichael AnteCu NguyenDalia DaujotyteElise D. BowmanNeelam SinhaKhadijah A. MitchellQingrong ChenChunhua YanPhillipe LoherDaoud MeerzamanEytan RuppinBríd M. RyanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Adriana Zingone Sanju Sinha Michael Ante Cu Nguyen Dalia Daujotyte Elise D. Bowman Neelam Sinha Khadijah A. Mitchell Qingrong Chen Chunhua Yan Phillipe Loher Daoud Meerzaman Eytan Ruppin Bríd M. Ryan A comprehensive map of alternative polyadenylation in African American and European American lung cancer patients
description	Alternative polyadenylation (APA) regulates the length of the 3′UTR of mRNA. Here, the authors describe a method to accurately measure APA in tumours and apply this method to investigate the differences in APA in African American and European American lung cancer samples.
format	article
author	Adriana Zingone Sanju Sinha Michael Ante Cu Nguyen Dalia Daujotyte Elise D. Bowman Neelam Sinha Khadijah A. Mitchell Qingrong Chen Chunhua Yan Phillipe Loher Daoud Meerzaman Eytan Ruppin Bríd M. Ryan
author_facet	Adriana Zingone Sanju Sinha Michael Ante Cu Nguyen Dalia Daujotyte Elise D. Bowman Neelam Sinha Khadijah A. Mitchell Qingrong Chen Chunhua Yan Phillipe Loher Daoud Meerzaman Eytan Ruppin Bríd M. Ryan
author_sort	Adriana Zingone
title	A comprehensive map of alternative polyadenylation in African American and European American lung cancer patients
title_short	A comprehensive map of alternative polyadenylation in African American and European American lung cancer patients
title_full	A comprehensive map of alternative polyadenylation in African American and European American lung cancer patients
title_fullStr	A comprehensive map of alternative polyadenylation in African American and European American lung cancer patients
title_full_unstemmed	A comprehensive map of alternative polyadenylation in African American and European American lung cancer patients
title_sort	comprehensive map of alternative polyadenylation in african american and european american lung cancer patients
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6fd436d5357e43f98a5a57bc9ef4218b
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A comprehensive map of alternative polyadenylation in African American and European American lung cancer patients

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