Nanomolar Inhibitors of <named-content content-type="genus-species">Trypanosoma brucei</named-content> RNA Triphosphatase
ABSTRACT Eukaryal taxa differ with respect to the structure and mechanism of the RNA triphosphatase (RTPase) component of the mRNA capping apparatus. Protozoa, fungi, and certain DNA viruses have a metal-dependent RTPase that belongs to the triphosphate tunnel metalloenzyme (TTM) superfamily. Becaus...
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| Main Authors: | , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2016
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| Subjects: | |
| Online Access: | https://doaj.org/article/6fe66f36ff9143d5983acf261b8d6d24 |
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