Single-cell RNA-seq of out-of-thaw mesenchymal stromal cells shows tissue-of-origin differences and inter-donor cell-cycle variations

Abstract Background Human Mesenchymal stromal cells (hMSCs) from various tissue sources are widely investigated in clinical trials. These MSCs are often administered to patients immediately after thawing the cryopreserved product (out-of-thaw), yet little is known about the single-cell transcriptomi...

Full description

Saved in:
Bibliographic Details
Main Authors: Camila Medrano-Trochez, Paramita Chatterjee, Pallab Pradhan, Hazel Y. Stevens, Molly E. Ogle, Edward A. Botchwey, Joanne Kurtzberg, Carolyn Yeago, Greg Gibson, Krishnendu Roy
Format: article
Language:EN
Published: BMC 2021
Subjects:
MSC
Online Access:https://doaj.org/article/6fea1886cd2e42f6a0a90995bb79307f
Tags: Add Tag
No Tags, Be the first to tag this record!