Targeting PTPRZ inhibits stem cell-like properties and tumorigenicity in glioblastoma cells
Abstract The R5 subfamily of receptor-type protein tyrosine phosphatases (RPTPs) comprises PTPRZ and PTPRG. A recent study on primary human glioblastomas suggested a close association between PTPRZ1 (human PTPRZ) expression and cancer stemness. However, the functional roles of PTPRZ activity in glio...
Guardado en:
Autores principales: | Akihiro Fujikawa, Hajime Sugawara, Taisaku Tanaka, Masahito Matsumoto, Kazuya Kuboyama, Ryoko Suzuki, Naomi Tanga, Atsuto Ogata, Makoto Masumura, Masaharu Noda |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/6fee56b055c14364a010dc2e318654be |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth
por: Yu Shi, et al.
Publicado: (2017) -
Ars2 promotes cell proliferation and tumorigenicity in glioblastoma through regulating miR-6798-3p
por: Yibiao Chen, et al.
Publicado: (2018) -
BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity
por: Rikke D. Rasmussen, et al.
Publicado: (2016) -
Author Correction: BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity
por: Rikke D. Rasmussen, et al.
Publicado: (2018) -
MicroRNA-146a limits tumorigenic inflammation in colorectal cancer
por: Lucien P. Garo, et al.
Publicado: (2021)