Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes

It is unclear what regulates gamete reprogramming competence. Here, the authors inject sperm into parthenogenetic embryos, generating viable offspring and show that mouse embryos in the mitotic cell cycle can reprogram sperm for full term development.

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Autores principales: Toru Suzuki, Maki Asami, Martin Hoffmann, Xin Lu, Miodrag Gužvić, Christoph A. Klein, Anthony C. F. Perry
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/6ffa962a410d45ca82f8dc8bc304e7be
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spelling oai:doaj.org-article:6ffa962a410d45ca82f8dc8bc304e7be2021-12-02T14:39:12ZMice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes10.1038/ncomms126762041-1723https://doaj.org/article/6ffa962a410d45ca82f8dc8bc304e7be2016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12676https://doaj.org/toc/2041-1723It is unclear what regulates gamete reprogramming competence. Here, the authors inject sperm into parthenogenetic embryos, generating viable offspring and show that mouse embryos in the mitotic cell cycle can reprogram sperm for full term development.Toru SuzukiMaki AsamiMartin HoffmannXin LuMiodrag GužvićChristoph A. KleinAnthony C. F. PerryNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Toru Suzuki
Maki Asami
Martin Hoffmann
Xin Lu
Miodrag Gužvić
Christoph A. Klein
Anthony C. F. Perry
Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes
description It is unclear what regulates gamete reprogramming competence. Here, the authors inject sperm into parthenogenetic embryos, generating viable offspring and show that mouse embryos in the mitotic cell cycle can reprogram sperm for full term development.
format article
author Toru Suzuki
Maki Asami
Martin Hoffmann
Xin Lu
Miodrag Gužvić
Christoph A. Klein
Anthony C. F. Perry
author_facet Toru Suzuki
Maki Asami
Martin Hoffmann
Xin Lu
Miodrag Gužvić
Christoph A. Klein
Anthony C. F. Perry
author_sort Toru Suzuki
title Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes
title_short Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes
title_full Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes
title_fullStr Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes
title_full_unstemmed Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes
title_sort mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/6ffa962a410d45ca82f8dc8bc304e7be
work_keys_str_mv AT torusuzuki miceproducedbymitoticreprogrammingofsperminjectedintohaploidparthenogenotes
AT makiasami miceproducedbymitoticreprogrammingofsperminjectedintohaploidparthenogenotes
AT martinhoffmann miceproducedbymitoticreprogrammingofsperminjectedintohaploidparthenogenotes
AT xinlu miceproducedbymitoticreprogrammingofsperminjectedintohaploidparthenogenotes
AT miodragguzvic miceproducedbymitoticreprogrammingofsperminjectedintohaploidparthenogenotes
AT christophaklein miceproducedbymitoticreprogrammingofsperminjectedintohaploidparthenogenotes
AT anthonycfperry miceproducedbymitoticreprogrammingofsperminjectedintohaploidparthenogenotes
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