Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes
It is unclear what regulates gamete reprogramming competence. Here, the authors inject sperm into parthenogenetic embryos, generating viable offspring and show that mouse embryos in the mitotic cell cycle can reprogram sperm for full term development.
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Nature Portfolio
2016
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oai:doaj.org-article:6ffa962a410d45ca82f8dc8bc304e7be2021-12-02T14:39:12ZMice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes10.1038/ncomms126762041-1723https://doaj.org/article/6ffa962a410d45ca82f8dc8bc304e7be2016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12676https://doaj.org/toc/2041-1723It is unclear what regulates gamete reprogramming competence. Here, the authors inject sperm into parthenogenetic embryos, generating viable offspring and show that mouse embryos in the mitotic cell cycle can reprogram sperm for full term development.Toru SuzukiMaki AsamiMartin HoffmannXin LuMiodrag GužvićChristoph A. KleinAnthony C. F. PerryNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016) |
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Science Q Toru Suzuki Maki Asami Martin Hoffmann Xin Lu Miodrag Gužvić Christoph A. Klein Anthony C. F. Perry Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes |
description |
It is unclear what regulates gamete reprogramming competence. Here, the authors inject sperm into parthenogenetic embryos, generating viable offspring and show that mouse embryos in the mitotic cell cycle can reprogram sperm for full term development. |
format |
article |
author |
Toru Suzuki Maki Asami Martin Hoffmann Xin Lu Miodrag Gužvić Christoph A. Klein Anthony C. F. Perry |
author_facet |
Toru Suzuki Maki Asami Martin Hoffmann Xin Lu Miodrag Gužvić Christoph A. Klein Anthony C. F. Perry |
author_sort |
Toru Suzuki |
title |
Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes |
title_short |
Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes |
title_full |
Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes |
title_fullStr |
Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes |
title_full_unstemmed |
Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes |
title_sort |
mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/6ffa962a410d45ca82f8dc8bc304e7be |
work_keys_str_mv |
AT torusuzuki miceproducedbymitoticreprogrammingofsperminjectedintohaploidparthenogenotes AT makiasami miceproducedbymitoticreprogrammingofsperminjectedintohaploidparthenogenotes AT martinhoffmann miceproducedbymitoticreprogrammingofsperminjectedintohaploidparthenogenotes AT xinlu miceproducedbymitoticreprogrammingofsperminjectedintohaploidparthenogenotes AT miodragguzvic miceproducedbymitoticreprogrammingofsperminjectedintohaploidparthenogenotes AT christophaklein miceproducedbymitoticreprogrammingofsperminjectedintohaploidparthenogenotes AT anthonycfperry miceproducedbymitoticreprogrammingofsperminjectedintohaploidparthenogenotes |
_version_ |
1718390719399329792 |