Update on ropinirole in the treatment of Parkinson’s disease

Holly A Shill, Mark StacySun Health Research Institute, Sun City, AZ, USA; Duke University and Medical Center, Durham, NC, USAAbstract: Ropinirole is a dopamine agonist, approved for use to treat symptoms of early and advanced Parkinson’s disease, is now available in a 24-hour formulat...

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Autores principales: Holly A Shill, Mark Stacy
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2008
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Acceso en línea:https://doaj.org/article/6ffc494fa7e0479cba2849d6edcf70f0
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spelling oai:doaj.org-article:6ffc494fa7e0479cba2849d6edcf70f02021-12-02T00:47:13ZUpdate on ropinirole in the treatment of Parkinson’s disease1176-63281178-2021https://doaj.org/article/6ffc494fa7e0479cba2849d6edcf70f02008-12-01T00:00:00Zhttp://www.dovepress.com/update-on-ropinirole-in-the-treatment-of-parkinsonrsquos-disease-a2745https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Holly A Shill, Mark StacySun Health Research Institute, Sun City, AZ, USA; Duke University and Medical Center, Durham, NC, USAAbstract: Ropinirole is a dopamine agonist, approved for use to treat symptoms of early and advanced Parkinson’s disease, is now available in a 24-hour formulation in addition to the immediate release version. This review discusses the mode of action of ropinirole and compares the pharmacokinetics of both formulations. Pivotal studies leading to the approval of both preparations are reviewed in terms of efficacy, dose range and side effects. Patient factors such as compliance are discussed in terms of the place for ropinirole in the armamentarium of Parkinson’s disease therapies.Keywords: ropinirole extended release, ropinirole immediate release Parkinson’s disease Holly A ShillMark StacyDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2009, Iss default, Pp 33-36 (2008)
institution DOAJ
collection DOAJ
language EN
topic Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Holly A Shill
Mark Stacy
Update on ropinirole in the treatment of Parkinson’s disease
description Holly A Shill, Mark StacySun Health Research Institute, Sun City, AZ, USA; Duke University and Medical Center, Durham, NC, USAAbstract: Ropinirole is a dopamine agonist, approved for use to treat symptoms of early and advanced Parkinson’s disease, is now available in a 24-hour formulation in addition to the immediate release version. This review discusses the mode of action of ropinirole and compares the pharmacokinetics of both formulations. Pivotal studies leading to the approval of both preparations are reviewed in terms of efficacy, dose range and side effects. Patient factors such as compliance are discussed in terms of the place for ropinirole in the armamentarium of Parkinson’s disease therapies.Keywords: ropinirole extended release, ropinirole immediate release Parkinson’s disease
format article
author Holly A Shill
Mark Stacy
author_facet Holly A Shill
Mark Stacy
author_sort Holly A Shill
title Update on ropinirole in the treatment of Parkinson’s disease
title_short Update on ropinirole in the treatment of Parkinson’s disease
title_full Update on ropinirole in the treatment of Parkinson’s disease
title_fullStr Update on ropinirole in the treatment of Parkinson’s disease
title_full_unstemmed Update on ropinirole in the treatment of Parkinson’s disease
title_sort update on ropinirole in the treatment of parkinson’s disease
publisher Dove Medical Press
publishDate 2008
url https://doaj.org/article/6ffc494fa7e0479cba2849d6edcf70f0
work_keys_str_mv AT hollyashill updateonropiniroleinthetreatmentofparkinsonamprsquosdisease
AT markstacy updateonropiniroleinthetreatmentofparkinsonamprsquosdisease
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