Update on ropinirole in the treatment of Parkinson’s disease
Holly A Shill, Mark StacySun Health Research Institute, Sun City, AZ, USA; Duke University and Medical Center, Durham, NC, USAAbstract: Ropinirole is a dopamine agonist, approved for use to treat symptoms of early and advanced Parkinson’s disease, is now available in a 24-hour formulat...
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Dove Medical Press
2008
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oai:doaj.org-article:6ffc494fa7e0479cba2849d6edcf70f02021-12-02T00:47:13ZUpdate on ropinirole in the treatment of Parkinson’s disease1176-63281178-2021https://doaj.org/article/6ffc494fa7e0479cba2849d6edcf70f02008-12-01T00:00:00Zhttp://www.dovepress.com/update-on-ropinirole-in-the-treatment-of-parkinsonrsquos-disease-a2745https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Holly A Shill, Mark StacySun Health Research Institute, Sun City, AZ, USA; Duke University and Medical Center, Durham, NC, USAAbstract: Ropinirole is a dopamine agonist, approved for use to treat symptoms of early and advanced Parkinson’s disease, is now available in a 24-hour formulation in addition to the immediate release version. This review discusses the mode of action of ropinirole and compares the pharmacokinetics of both formulations. Pivotal studies leading to the approval of both preparations are reviewed in terms of efficacy, dose range and side effects. Patient factors such as compliance are discussed in terms of the place for ropinirole in the armamentarium of Parkinson’s disease therapies.Keywords: ropinirole extended release, ropinirole immediate release Parkinson’s disease Holly A ShillMark StacyDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2009, Iss default, Pp 33-36 (2008) |
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Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
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Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Holly A Shill Mark Stacy Update on ropinirole in the treatment of Parkinson’s disease |
description |
Holly A Shill, Mark StacySun Health Research Institute, Sun City, AZ, USA; Duke University and Medical Center, Durham, NC, USAAbstract: Ropinirole is a dopamine agonist, approved for use to treat symptoms of early and advanced Parkinson’s disease, is now available in a 24-hour formulation in addition to the immediate release version. This review discusses the mode of action of ropinirole and compares the pharmacokinetics of both formulations. Pivotal studies leading to the approval of both preparations are reviewed in terms of efficacy, dose range and side effects. Patient factors such as compliance are discussed in terms of the place for ropinirole in the armamentarium of Parkinson’s disease therapies.Keywords: ropinirole extended release, ropinirole immediate release Parkinson’s disease |
format |
article |
author |
Holly A Shill Mark Stacy |
author_facet |
Holly A Shill Mark Stacy |
author_sort |
Holly A Shill |
title |
Update on ropinirole in the treatment of Parkinson’s disease |
title_short |
Update on ropinirole in the treatment of Parkinson’s disease |
title_full |
Update on ropinirole in the treatment of Parkinson’s disease |
title_fullStr |
Update on ropinirole in the treatment of Parkinson’s disease |
title_full_unstemmed |
Update on ropinirole in the treatment of Parkinson’s disease |
title_sort |
update on ropinirole in the treatment of parkinson’s disease |
publisher |
Dove Medical Press |
publishDate |
2008 |
url |
https://doaj.org/article/6ffc494fa7e0479cba2849d6edcf70f0 |
work_keys_str_mv |
AT hollyashill updateonropiniroleinthetreatmentofparkinsonamprsquosdisease AT markstacy updateonropiniroleinthetreatmentofparkinsonamprsquosdisease |
_version_ |
1718403503470149632 |