Uncovering the molecular machinery of the human spindle--an integration of wet and dry systems biology.

Uncovering the molecular machinery of the human spindle--an integration of wet and dry systems biology.

The mitotic spindle is an essential molecular machine involved in cell division, whose composition has been studied extensively by detailed cellular biology, high-throughput proteomics, and RNA interference experiments. However, because of its dynamic organization and complex regulation it is diffic...

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Autores principales: Ana M Rojas, Anna Santamaria, Rainer Malik, Thomas Skøt Jensen, Roman Körner, Ian Morilla, David de Juan, Martin Krallinger, Daniel Aaen Hansen, Robert Hoffmann, Jonathan Lees, Adam Reid, Corin Yeats, Anja Wehner, Sabine Elowe, Andrew B Clegg, Søren Brunak, Erich A Nigg, Christine Orengo, Alfonso Valencia, Juan A G Ranea
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/70153f80d41f49f28dad5fc2de9963d1
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