Postoperative Candida Infection following Complex Periocular Reconstruction

Summary:. Postoperative candida infection is a rarely reported complication in cutaneous surgery, although it may develop more often in particular clinical settings. We present a 59-year-old woman with a well-controlled human immunodeficiency virus infection. She developed a bright red eruption with...

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Autores principales:	Luke S. Wallis, MD, Carolyn M. Stull, MD, Uros Rakita, MSc, Solomiya Grushchak, MD, Amjad Z. Ahmad, MD, Aleksandar L. Krunic, MD, PhD
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer 2021
Materias:	Surgery RD1-811
Acceso en línea:	https://doaj.org/article/70318720a8c541b6824693caa05c2e32
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spelling	oai:doaj.org-article:70318720a8c541b6824693caa05c2e322021-11-25T07:58:04ZPostoperative Candida Infection following Complex Periocular Reconstruction2169-757410.1097/GOX.0000000000003891https://doaj.org/article/70318720a8c541b6824693caa05c2e322021-11-01T00:00:00Zhttp://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000003891https://doaj.org/toc/2169-7574Summary:. Postoperative candida infection is a rarely reported complication in cutaneous surgery, although it may develop more often in particular clinical settings. We present a 59-year-old woman with a well-controlled human immunodeficiency virus infection. She developed a bright red eruption with satellite pustules 2 weeks after excision of recurrent lentigo maligna melanoma of the left lower eyelid and periocular region. Due to defect size and complexity of the reconstruction (glabellar transposition flap, Hughes flap, composite graft from upper contralateral eyelid, and full-thickness skin graft from ipsilateral retroauricular region), she was placed on prophylactic oral amoxicillin-clavulanic acid and topical bacitracin and polymyxin. Immediate postoperative course was unremarkable, and sutures were removed after 7 days. Three days later, she developed bright red erythema and pustules within the surgical site and complained of burning. Empirically she was switched to topical gentamicin and oral ciprofloxacin, and later to linezolid, due to inadequate response. Wound culture grew Candida albicans sensitive to fluconazole and voriconazole. After oral fluconazole and topical clotrimazole initiation, the patient rapidly improved. The graft remained viable and apart from small partial dehiscence on the cheek, the healing was unremarkable. Apart from the case presentation, we also discuss different factors associated with postoperative candida infection, including immunocompromised status, surgical procedure location, and postoperative antibiotic use. Early recognition and treatment of postoperative candida infections are crucial to prevent delayed healing and associated morbidity.Luke S. Wallis, MDCarolyn M. Stull, MDUros Rakita, MScSolomiya Grushchak, MDAmjad Z. Ahmad, MDAleksandar L. Krunic, MD, PhDWolters KluwerarticleSurgeryRD1-811ENPlastic and Reconstructive Surgery, Global Open, Vol 9, Iss 11, p e3891 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Surgery RD1-811
spellingShingle	Surgery RD1-811 Luke S. Wallis, MD Carolyn M. Stull, MD Uros Rakita, MSc Solomiya Grushchak, MD Amjad Z. Ahmad, MD Aleksandar L. Krunic, MD, PhD Postoperative Candida Infection following Complex Periocular Reconstruction
description	Summary:. Postoperative candida infection is a rarely reported complication in cutaneous surgery, although it may develop more often in particular clinical settings. We present a 59-year-old woman with a well-controlled human immunodeficiency virus infection. She developed a bright red eruption with satellite pustules 2 weeks after excision of recurrent lentigo maligna melanoma of the left lower eyelid and periocular region. Due to defect size and complexity of the reconstruction (glabellar transposition flap, Hughes flap, composite graft from upper contralateral eyelid, and full-thickness skin graft from ipsilateral retroauricular region), she was placed on prophylactic oral amoxicillin-clavulanic acid and topical bacitracin and polymyxin. Immediate postoperative course was unremarkable, and sutures were removed after 7 days. Three days later, she developed bright red erythema and pustules within the surgical site and complained of burning. Empirically she was switched to topical gentamicin and oral ciprofloxacin, and later to linezolid, due to inadequate response. Wound culture grew Candida albicans sensitive to fluconazole and voriconazole. After oral fluconazole and topical clotrimazole initiation, the patient rapidly improved. The graft remained viable and apart from small partial dehiscence on the cheek, the healing was unremarkable. Apart from the case presentation, we also discuss different factors associated with postoperative candida infection, including immunocompromised status, surgical procedure location, and postoperative antibiotic use. Early recognition and treatment of postoperative candida infections are crucial to prevent delayed healing and associated morbidity.
format	article
author	Luke S. Wallis, MD Carolyn M. Stull, MD Uros Rakita, MSc Solomiya Grushchak, MD Amjad Z. Ahmad, MD Aleksandar L. Krunic, MD, PhD
author_facet	Luke S. Wallis, MD Carolyn M. Stull, MD Uros Rakita, MSc Solomiya Grushchak, MD Amjad Z. Ahmad, MD Aleksandar L. Krunic, MD, PhD
author_sort	Luke S. Wallis, MD
title	Postoperative Candida Infection following Complex Periocular Reconstruction
title_short	Postoperative Candida Infection following Complex Periocular Reconstruction
title_full	Postoperative Candida Infection following Complex Periocular Reconstruction
title_fullStr	Postoperative Candida Infection following Complex Periocular Reconstruction
title_full_unstemmed	Postoperative Candida Infection following Complex Periocular Reconstruction
title_sort	postoperative candida infection following complex periocular reconstruction
publisher	Wolters Kluwer
publishDate	2021
url	https://doaj.org/article/70318720a8c541b6824693caa05c2e32
work_keys_str_mv	AT lukeswallismd postoperativecandidainfectionfollowingcomplexperiocularreconstruction AT carolynmstullmd postoperativecandidainfectionfollowingcomplexperiocularreconstruction AT urosrakitamsc postoperativecandidainfectionfollowingcomplexperiocularreconstruction AT solomiyagrushchakmd postoperativecandidainfectionfollowingcomplexperiocularreconstruction AT amjadzahmadmd postoperativecandidainfectionfollowingcomplexperiocularreconstruction AT aleksandarlkrunicmdphd postoperativecandidainfectionfollowingcomplexperiocularreconstruction
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Postoperative Candida Infection following Complex Periocular Reconstruction

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