Overlapping roles of spliceosomal components SF3B1 and PHF5A in rice splicing regulation

Butt et al. used CRISPR-mediated directed evolution to generate rice mutants for the spliceosome components SF3B1 and PHF5A. They demonstrate that these mutants have different levels of sensitivity to salt treatments and suggest that the strategies they employed can be used in the future to study fu...

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Autores principales:	Haroon Butt, Jeremie Bazin, Sahar Alshareef, Ayman Eid, Moussa Benhamed, Anireddy S. N. Reddy, Martin Crespi, Magdy M. Mahfouz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/703302990f754f29a4eed38060c57568
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spelling	oai:doaj.org-article:703302990f754f29a4eed38060c575682021-12-02T15:38:22ZOverlapping roles of spliceosomal components SF3B1 and PHF5A in rice splicing regulation10.1038/s42003-021-02051-y2399-3642https://doaj.org/article/703302990f754f29a4eed38060c575682021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02051-yhttps://doaj.org/toc/2399-3642Butt et al. used CRISPR-mediated directed evolution to generate rice mutants for the spliceosome components SF3B1 and PHF5A. They demonstrate that these mutants have different levels of sensitivity to salt treatments and suggest that the strategies they employed can be used in the future to study functions of redundant paralogs in plants.Haroon ButtJeremie BazinSahar AlshareefAyman EidMoussa BenhamedAnireddy S. N. ReddyMartin CrespiMagdy M. MahfouzNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Haroon Butt Jeremie Bazin Sahar Alshareef Ayman Eid Moussa Benhamed Anireddy S. N. Reddy Martin Crespi Magdy M. Mahfouz Overlapping roles of spliceosomal components SF3B1 and PHF5A in rice splicing regulation
description	Butt et al. used CRISPR-mediated directed evolution to generate rice mutants for the spliceosome components SF3B1 and PHF5A. They demonstrate that these mutants have different levels of sensitivity to salt treatments and suggest that the strategies they employed can be used in the future to study functions of redundant paralogs in plants.
format	article
author	Haroon Butt Jeremie Bazin Sahar Alshareef Ayman Eid Moussa Benhamed Anireddy S. N. Reddy Martin Crespi Magdy M. Mahfouz
author_facet	Haroon Butt Jeremie Bazin Sahar Alshareef Ayman Eid Moussa Benhamed Anireddy S. N. Reddy Martin Crespi Magdy M. Mahfouz
author_sort	Haroon Butt
title	Overlapping roles of spliceosomal components SF3B1 and PHF5A in rice splicing regulation
title_short	Overlapping roles of spliceosomal components SF3B1 and PHF5A in rice splicing regulation
title_full	Overlapping roles of spliceosomal components SF3B1 and PHF5A in rice splicing regulation
title_fullStr	Overlapping roles of spliceosomal components SF3B1 and PHF5A in rice splicing regulation
title_full_unstemmed	Overlapping roles of spliceosomal components SF3B1 and PHF5A in rice splicing regulation
title_sort	overlapping roles of spliceosomal components sf3b1 and phf5a in rice splicing regulation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/703302990f754f29a4eed38060c57568
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Overlapping roles of spliceosomal components SF3B1 and PHF5A in rice splicing regulation

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