Effect of short-term fasting on the expression of ACTH (cMC2) receptor in the adrenal glands of chicken (Gallus domesticus)

<b>Domestic hen is a full model in terms of stress and adrenal function. The main hormone produced by the hens’ adrenals is corticosterone, synthesized and secreted by stimulating the HPA axis during stress. Direct activation of adrenal activity is conditioned by ACTH, which binds to the melan...

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Autores principales:	Izabela Szpręgiel, Danuta Wronska
Formato:	article
Lenguaje:	EN PL
Publicado:	Polish Society of Animal Production 2021
Materias:	adrenal glands starvation corticosterone melanocortin receptor cMC2 chicken cMC2 Zoology QL1-991
Acceso en línea:	https://doaj.org/article/7034ae594a014f1fac83e2743b6dced3
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id	oai:doaj.org-article:7034ae594a014f1fac83e2743b6dced3
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spelling	oai:doaj.org-article:7034ae594a014f1fac83e2743b6dced32021-11-10T16:58:22ZEffect of short-term fasting on the expression of ACTH (cMC2) receptor in the adrenal glands of chicken (Gallus domesticus)1733-73052719-393410.5604/01.3001.0015.5024https://doaj.org/article/7034ae594a014f1fac83e2743b6dced32021-09-01T00:00:00Zhttp://zootechnical.com/gicid/01.3001.0015.5024http://zootechnical.com/gicid/pdf/01.3001.0015.5024https://doaj.org/toc/1733-7305https://doaj.org/toc/2719-3934<b>Domestic hen is a full model in terms of stress and adrenal function. The main hormone produced by the hens’ adrenals is corticosterone, synthesized and secreted by stimulating the HPA axis during stress. Direct activation of adrenal activity is conditioned by ACTH, which binds to the melanocortin receptor cMC2 in adrenals. It stimulates the synthesis and release of corticosterone. One of the factors that stimulate the HPA axis activity is the starvation, to which the hen is very sensitive. The purpose of this study was to determine the ACTH receptor cMC2 expression in the hens’ adrenals during the short-term fasting and after restoring the proper level of nutrition (refeeding). The results of the experiment show that 24-hour of food deprivation is stressful for the hen, as indicated by increased concentrations of corticosterone in the adrenals and in blood plasma. Changes in cMC2R expression and level of corticosterone in the adrenals during fasting and refeeding indicate a rapid increase of HPA axis activity in response to differentiated levels of nutrition. The results of this experiment confirm the direct effect of ACTH on the avian adrenals in corticosterone release. Izabela SzpręgielDanuta WronskaPolish Society of Animal Productionarticleadrenal glandsstarvationcorticosteronemelanocortin receptor cMC2 chickencMC2ZoologyQL1-991ENPLRoczniki Naukowe Polskiego Towarzystwa Zootechnicznego, Vol 17, Iss 3, Pp 31-45 (2021)
institution	DOAJ
collection	DOAJ
language	EN PL
topic	adrenal glands starvation corticosterone melanocortin receptor cMC2 chicken cMC2 Zoology QL1-991
spellingShingle	adrenal glands starvation corticosterone melanocortin receptor cMC2 chicken cMC2 Zoology QL1-991 Izabela Szpręgiel Danuta Wronska Effect of short-term fasting on the expression of ACTH (cMC2) receptor in the adrenal glands of chicken (Gallus domesticus)
description	<b>Domestic hen is a full model in terms of stress and adrenal function. The main hormone produced by the hens’ adrenals is corticosterone, synthesized and secreted by stimulating the HPA axis during stress. Direct activation of adrenal activity is conditioned by ACTH, which binds to the melanocortin receptor cMC2 in adrenals. It stimulates the synthesis and release of corticosterone. One of the factors that stimulate the HPA axis activity is the starvation, to which the hen is very sensitive. The purpose of this study was to determine the ACTH receptor cMC2 expression in the hens’ adrenals during the short-term fasting and after restoring the proper level of nutrition (refeeding). The results of the experiment show that 24-hour of food deprivation is stressful for the hen, as indicated by increased concentrations of corticosterone in the adrenals and in blood plasma. Changes in cMC2R expression and level of corticosterone in the adrenals during fasting and refeeding indicate a rapid increase of HPA axis activity in response to differentiated levels of nutrition. The results of this experiment confirm the direct effect of ACTH on the avian adrenals in corticosterone release.
format	article
author	Izabela Szpręgiel Danuta Wronska
author_facet	Izabela Szpręgiel Danuta Wronska
author_sort	Izabela Szpręgiel
title	Effect of short-term fasting on the expression of ACTH (cMC2) receptor in the adrenal glands of chicken (Gallus domesticus)
title_short	Effect of short-term fasting on the expression of ACTH (cMC2) receptor in the adrenal glands of chicken (Gallus domesticus)
title_full	Effect of short-term fasting on the expression of ACTH (cMC2) receptor in the adrenal glands of chicken (Gallus domesticus)
title_fullStr	Effect of short-term fasting on the expression of ACTH (cMC2) receptor in the adrenal glands of chicken (Gallus domesticus)
title_full_unstemmed	Effect of short-term fasting on the expression of ACTH (cMC2) receptor in the adrenal glands of chicken (Gallus domesticus)
title_sort	effect of short-term fasting on the expression of acth (cmc2) receptor in the adrenal glands of chicken (gallus domesticus)
publisher	Polish Society of Animal Production
publishDate	2021
url	https://doaj.org/article/7034ae594a014f1fac83e2743b6dced3
work_keys_str_mv	AT izabelaszpregiel effectofshorttermfastingontheexpressionofacthcmc2receptorintheadrenalglandsofchickengallusdomesticus AT danutawronska effectofshorttermfastingontheexpressionofacthcmc2receptorintheadrenalglandsofchickengallusdomesticus
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Effect of short-term fasting on the expression of ACTH (cMC2) receptor in the adrenal glands of chicken (Gallus domesticus)

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