Comparative diagnostic accuracy of ACE-III and MoCA for detecting mild cognitive impairment
Bian-Rong Wang,1 Hui-Fen Zheng,1 Chang Xu,1 Yi Sun,1 Ying-Dong Zhang,2 Jian-Quan Shi2 1Department of Neurology, Geriatric Hospital of Nanjing Medical University, Nanjing, Jiangsu Province 210024, People’s Republic of China; 2Department of Neurology, Nanjing First Hospital, Nanjing Medical...
Guardado en:
| Autores principales: | , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Dove Medical Press
2019
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/703612f6ce8b489a82351d312407efb1 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:703612f6ce8b489a82351d312407efb1 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:703612f6ce8b489a82351d312407efb12021-12-02T07:27:25ZComparative diagnostic accuracy of ACE-III and MoCA for detecting mild cognitive impairment1178-2021https://doaj.org/article/703612f6ce8b489a82351d312407efb12019-09-01T00:00:00Zhttps://www.dovepress.com/comparative-diagnostic-accuracy-of-ace-iii-and-moca-for-detecting-mild-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Bian-Rong Wang,1 Hui-Fen Zheng,1 Chang Xu,1 Yi Sun,1 Ying-Dong Zhang,2 Jian-Quan Shi2 1Department of Neurology, Geriatric Hospital of Nanjing Medical University, Nanjing, Jiangsu Province 210024, People’s Republic of China; 2Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu Province 210006, People’s Republic of ChinaCorrespondence: Ying-Dong Zhang; Jian-Quan ShiDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, No. 68, Changle Road, Nanjing, Jiangsu Province 210006, People’s Republic of ChinaTel +86 0 258 772 6218; +86 0 258 772 6224Email zhangyingdong@aliyun.com; myxiyi_0717@163.comObjective: The aim of this study was to validate the reliability of the Chinese version of Addenbrooke’s Cognitive Examination III (ACE-III) for detecting mild cognitive impairment. Furthermore, the present study compares the diagnostic accuracy of ACE-III with that of Montreal Cognitive Assessment (MoCA).Methods: One hundred and twenty patients with MCI and 136 healthy controls were included in the study. All patients were evaluated by the Chinese version of ACE-III, MoCA and MMSE.Results: Subjects in the control group showed better performance in ACE-III total score and its subdomain scores than those in the MCI group. There was a significantly positive correlation between ACE-III total score and MoCA score. Meanwhile, there was also a significantly positive correlation between ACE-III total score and MMSE score. For ACE-III total score, a cut-off point of 85 yielded a sensitivity of 97.3% and a specificity of 90.7%. The AUC for ACE-III total score was 0.978. For MoCA, a cut-off point of 23 yielded a sensitivity of 86.5% and a specificity of 97.7%. The AUC for MoCA was 0.961. There were no significant differences in diagnostic accuracy between ACE-III and MoCA.Conclusion: The present findings support that both ACE-III and MoCA are useful for detecting MCI in early stages.Keywords: Addenbrooke’s Cognitive Examination III, Montreal Cognitive Assessment, mild cognitive impairment, cognitive screening, Chinese Wang BRZheng HFXu CSun YZhang YDShi JQDove Medical PressarticleAddenbrooke’s Cognitive Examination IIIMontreal Cognitive AssessmentMild cognitive impairmentCognitive screeningChineseNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 15, Pp 2647-2653 (2019) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Addenbrooke’s Cognitive Examination III Montreal Cognitive Assessment Mild cognitive impairment Cognitive screening Chinese Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
| spellingShingle |
Addenbrooke’s Cognitive Examination III Montreal Cognitive Assessment Mild cognitive impairment Cognitive screening Chinese Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Wang BR Zheng HF Xu C Sun Y Zhang YD Shi JQ Comparative diagnostic accuracy of ACE-III and MoCA for detecting mild cognitive impairment |
| description |
Bian-Rong Wang,1 Hui-Fen Zheng,1 Chang Xu,1 Yi Sun,1 Ying-Dong Zhang,2 Jian-Quan Shi2 1Department of Neurology, Geriatric Hospital of Nanjing Medical University, Nanjing, Jiangsu Province 210024, People’s Republic of China; 2Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu Province 210006, People’s Republic of ChinaCorrespondence: Ying-Dong Zhang; Jian-Quan ShiDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, No. 68, Changle Road, Nanjing, Jiangsu Province 210006, People’s Republic of ChinaTel +86 0 258 772 6218; +86 0 258 772 6224Email zhangyingdong@aliyun.com; myxiyi_0717@163.comObjective: The aim of this study was to validate the reliability of the Chinese version of Addenbrooke’s Cognitive Examination III (ACE-III) for detecting mild cognitive impairment. Furthermore, the present study compares the diagnostic accuracy of ACE-III with that of Montreal Cognitive Assessment (MoCA).Methods: One hundred and twenty patients with MCI and 136 healthy controls were included in the study. All patients were evaluated by the Chinese version of ACE-III, MoCA and MMSE.Results: Subjects in the control group showed better performance in ACE-III total score and its subdomain scores than those in the MCI group. There was a significantly positive correlation between ACE-III total score and MoCA score. Meanwhile, there was also a significantly positive correlation between ACE-III total score and MMSE score. For ACE-III total score, a cut-off point of 85 yielded a sensitivity of 97.3% and a specificity of 90.7%. The AUC for ACE-III total score was 0.978. For MoCA, a cut-off point of 23 yielded a sensitivity of 86.5% and a specificity of 97.7%. The AUC for MoCA was 0.961. There were no significant differences in diagnostic accuracy between ACE-III and MoCA.Conclusion: The present findings support that both ACE-III and MoCA are useful for detecting MCI in early stages.Keywords: Addenbrooke’s Cognitive Examination III, Montreal Cognitive Assessment, mild cognitive impairment, cognitive screening, Chinese
|
| format |
article |
| author |
Wang BR Zheng HF Xu C Sun Y Zhang YD Shi JQ |
| author_facet |
Wang BR Zheng HF Xu C Sun Y Zhang YD Shi JQ |
| author_sort |
Wang BR |
| title |
Comparative diagnostic accuracy of ACE-III and MoCA for detecting mild cognitive impairment |
| title_short |
Comparative diagnostic accuracy of ACE-III and MoCA for detecting mild cognitive impairment |
| title_full |
Comparative diagnostic accuracy of ACE-III and MoCA for detecting mild cognitive impairment |
| title_fullStr |
Comparative diagnostic accuracy of ACE-III and MoCA for detecting mild cognitive impairment |
| title_full_unstemmed |
Comparative diagnostic accuracy of ACE-III and MoCA for detecting mild cognitive impairment |
| title_sort |
comparative diagnostic accuracy of ace-iii and moca for detecting mild cognitive impairment |
| publisher |
Dove Medical Press |
| publishDate |
2019 |
| url |
https://doaj.org/article/703612f6ce8b489a82351d312407efb1 |
| work_keys_str_mv |
AT wangbr comparativediagnosticaccuracyofaceiiiandmocafordetectingmildcognitiveimpairment AT zhenghf comparativediagnosticaccuracyofaceiiiandmocafordetectingmildcognitiveimpairment AT xuc comparativediagnosticaccuracyofaceiiiandmocafordetectingmildcognitiveimpairment AT suny comparativediagnosticaccuracyofaceiiiandmocafordetectingmildcognitiveimpairment AT zhangyd comparativediagnosticaccuracyofaceiiiandmocafordetectingmildcognitiveimpairment AT shijq comparativediagnosticaccuracyofaceiiiandmocafordetectingmildcognitiveimpairment |
| _version_ |
1718399407685107712 |